Protein Information

Name 3 hydroxy 3 methylglutaryl coenzyme A reductase
Synonyms 3 Hydroxy 3 methylglutaryl CoA reductase; 3 Hydroxy 3 methylglutaryl Coenzyme A reductase; Beta hydroxy beta methyl glutaryl CoA reductase; HMG CoA reductase; HMG Coenzyme A reductase; HMGCR; 3 Hydroxy 3 methylglutaryl Coenzyme A reductases; Beta hydroxy beta methyl glutaryl CoA reductases…

Compound Information

Name sodium fluoride
CAS sodium fluoride (NaF)

Reference List

PubMed Abstract RScore(About this table)
16194044 Okopien B, Krysiak R, Labuzek K, Herman ZS: [Anabolic therapy of osteoporosis] . Pol Merkur Lekarski. 2005 Jul;19(109):118-21.

In the present study we describe in details sodium fluoride, 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins), growth hormone, insulin-like growth factor I, and parathormone and its analogues, describing their mechanism of action and adverse effects.
31(0,1,1,1) Details
16124390 Okopien B, Krysiak R, Labuzek K, Herman ZS: [Anabolic therapy in osteoporosis--part 1] . Pol Merkur Lekarski. 2005 Jun;18(108):712-4.

In the present study we describe in details sodium fluoride, 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins), growth hormone, insulin-like growth factor I, and parathormone and its analogues, describing their mechanism of action and adverse effects.
31(0,1,1,1) Details
9245257 Douglas P, Pigaglio E, Ferrer A, Halfords NG, MacKintosh C: Three spinach leaf nitrate reductase-3-hydroxy-3-methylglutaryl-CoA reductase kinases that are required by reversible phosphorylation and/or Ca2+ ions. Biochem J. 1997 Jul 1;325 ( Pt 1):101-9.

2(0,0,0,2) Details
10946302 Sadeghi MM, Collinge M, Pardi R, Bender JR: Simvastatin modulates cytokine-mediated endothelial cell adhesion molecule induction: involvement of an inhibitory G protein. J Immunol. 2000 Sep 1;165(5):2712-8.


We studied the effect of a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, simvastatin, on cytokine-induced expression of CAMs in HUVEC.
1(0,0,0,1) Details