| Name | protein tyrosine phosphatases |
|---|---|
| Synonyms | DUSP16; DUSP16 protein; Dual specificity phosphatase 16; Dual specificity protein phosphatase 16; MAP kinase phosphatase 7; MAPK phosphatase 7; MKP 7; MKP7… |
| Name | sodium fluoride |
|---|---|
| CAS | sodium fluoride (NaF) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12538343 | Chuang SM, Wang IC, Hwua YS, Yang JL: Short-term depletion of catalase suppresses cadmium-elicited c-Jun N-terminal kinase activation and apoptosis: role of protein phosphatases. Carcinogenesis. 2003 Jan;24(1):7-15. Intriguingly, sodium fluoride or okadaic acid, inhibitors for serine/threonine protein phosphatases (PP), recovered the JNK activity in CL3 cells exposed to Cd plus 3AT; however, the protein tyrosine phosphatases inhibitor orthovanadate did not. |
31(0,1,1,1) | Details |
| 10470129 | Yoshida J, Takamura S, Ishibashi T, Nishio M: Antiproliferative and apoptosis-inducing effects of an antitumor glycoprotein from Streptococcus pyogenes. Anticancer Res. 1999 May-Jun;19(3A):1865-71. The SAGP-induced DNA fragmentation in Meth A cells was augmented by herbimycin A, an inhibitor of protein tyrosine kinase, and prevented by orthovanadate, an inhibitor of protein tyrosine phosphatase. |
2(0,0,0,2) | Details |
| 10446377 | Roknabadi SM, Bose SK, Taneja V: A thiol 100 kDa, tetrameric acid phosphatase from lentil, Lens esculenta, seeds with the characteristics of protein tyrosine phosphatases. Biochim Biophys Acta. 1999 Aug 17;1433(1-2):272-80. -O- 3'-AMP and pNPP hydrolysis is potently inhibited by micromolar orthovanadate and also to nearly the same extent by sodium fluoride, and metal ions. |
2(0,0,0,2) | Details |
| 9079918 | McCartney B, Howell LD, Kennelly PJ, Potts M: Protein tyrosine phosphorylation in the cyanobacterium Anabaena sp. strain PCC 7120. J Bacteriol. 1997 Apr;179(7):2314-8. Anabaena sp. strain PCC 7120 cell extracts contained a protein tyrosine phosphatase activity that was abolished in the presence of orthovanadate and inhibited significantly by the sulfhydryl-modifying agents p-hydroxymercuriphenylsulfonic acid and p-hydroxymercuribenzoate as well as by The P-Tyr content of the three major P-Tyr proteins and several minor proteins increased with their time of incubation in the presence of Mg-ATP and the protein phosphatase inhibitors orthovanadate and sodium fluoride. |
1(0,0,0,1) | Details |
| 8900457 | Lau TE, Rodriguez MA: A protein tyrosine kinase associated with the ATP-dependent inactivation of adipose diacylglycerol acyltransferase. Lipids. 1996 Mar;31(3):277-83. These results suggest that a protein tyrosine kinase, in concert with a protein tyrosine phosphatase, may regulate the activities of DGAT and GPAT by a phosphorylation-dephosphorylation mechanism. |
1(0,0,0,1) | Details |
| 10467181 | Nishito Y, Usui H, Tanabe O, Shimizu M, Takeda M: Interconversion of Mn (2+)-dependent and -independent protein phosphatase 2A from human erythrocytes: role of Zn (2+) and Fe (2+) in protein phosphatase 2A. J Biochem. 1999 Sep;126(3):632-8. The Mn (2+)-dependent protein-tyrosine phosphatase (PTP) activity of C'A' was about 70-fold higher than that of CA. |
1(0,0,0,1) | Details |
| 12151384 | Peters MA, Jackson DC, Crabb BS, Browning GF: Chicken anemia virus VP2 is a novel dual specificity protein phosphatase. . J Biol Chem. 2002 Oct 18;277(42):39566-73. Epub 2002 Jul 31. Both CAV GST-VP2 and TLMV GST-ORF2 fusion proteins possessed S/T PPase activity, which was specifically inhibited by 50 mm sodium fluoride. We show that the CAV VP2 amino acid sequence has some similarity to a number of eukaryotic, receptor, protein-tyrosine phosphatase (PTPase) alpha proteins as well as to a cluster of human TT viruses within the Sanban group. |
1(0,0,0,1) | Details |