Protein Information

Name AQP3
Synonyms AQP 3; AQP3; Aquaporin 3; GIL; aquaporin 3 (GIL blood group); aquaporin 3 (Gill blood group); Aquaporin 3s; aquaporin 3 (GIL blood group)s…

Compound Information

Name sodium fluoride
CAS sodium fluoride (NaF)

Reference List

PubMed Abstract RScore(About this table)
12745716 Yeum CH, Kim SW, Lee SC, Choi KC, Ahn KY, Lee J: Diminished expression of aquaporin water channels in ureteral-obstructed kidney in rats. Scand J Urol Nephrol. 2003;37(2):99-105.

The expression of AQP1 and AQP3 was decreased in the outer medulla and inner medulla. cAMP generation in response to AVP, sodium fluoride or forskolin was greatly decreased.
6(0,0,1,1) Details
11316845 Kim SW, Lee JU, Nah MY, Kang DG, Ahn KY, Lee HS, Choi KC: Cisplatin decreases the abundance of aquaporin water channels in rat kidney. J Am Soc Nephrol. 2001 May;12(5):875-82.

However, the cyclic adenosine monophosphate generation in response to forskolin was not affected, whereas that to sodium fluoride was diminished significantly.
Four d later, the expression of AQP1, AQP2, and AQP3 proteins was determined in the kidney.
3(0,0,0,3) Details
11562400 Kim SW, Cho SH, Oh BS, Yeum CH, Choi KC, Ahn KY, Lee J: Diminished renal expression of aquaporin water channels in rats with experimental bilateral ureteral obstruction. J Am Soc Nephrol. 2001 Oct;12(10):2019-28.

The protein expression of G (salpha) was decreased in the cortex, outer medulla, and inner medulla, whereas that of adenylyl cyclase VI was decreased in the outer and inner medullae. cAMP generation stimulated by arginine vasopressin was decreased in the cortex, outer medulla, and inner medulla. cAMP generation in response to forskolin was decreased in the outer and inner medullae, whereas that in response to sodium fluoride was decreased in the cortex, outer medulla, and inner medulla.
In the obstructed kidneys, the expression of AQP1 to AQP3 was decreased in the cortex, outer medulla, and inner medulla, whereas that of AQP4 was decreased in the inner medulla.
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11388643 Lee J, Yoo KS, Kang DG, Kim SW, Choi KC: Gentamicin decreases the abundance of aquaporin water channels in rat kidney. Jpn J Pharmacol. 2001 Apr;85(4):391-8.

The protein expression of AQP1 as well as that of AQP3 was also decreased in the cortex by treatment with the highest dose of gentamicin.
The cAMP generation in response to arginine vasopressin or sodium fluoride was decreased by gentamicin, while that to forskolin was not significantly altered.
1(0,0,0,1) Details
11574818 Kim SW, Yeum CH, Kim S, Oh Y, Choi KC, Lee J: Amphotericin B decreases adenylyl cyclase activity and aquaporin-2 expression in rat kidney. J Lab Clin Med. 2001 Oct;138(4):243-9.


The cAMP generation in response to AVP or sodium fluoride was decreased, whereas that to forskolin was not significantly altered.
0(0,0,0,0) Details
12208125 Yeum CH, Kim SW, Kim NH, Choi KC, Lee J: Increased expression of aquaporin water channels in hypothyroid rat kidney. Pharmacol Res. 2002 Jul;46(1):85-8.


The adenylyl cyclase activity provoked by arginine vasopressin (AVP), sodium fluoride, or forskolin was blunted in the hypothyroid kidney, while plasma levels of AVP were not significantly changed.
0(0,0,0,0) Details