| Name | Raf 1 |
|---|---|
| Synonyms | C RAF; CRAF; Oncogene MIL; Oncogene RAF1; RAF; RAF proto oncogene serine/threonine protein kinase; RAF1; RAF1 protein… |
| Name | sodium fluoride |
|---|---|
| CAS | sodium fluoride (NaF) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11494123 | Jaumot M, Hancock JF: Protein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactions. Oncogene. 2001 Jul 5;20(30):3949-58. General serine- phosphatase inhibitors such sodium fluoride, or ss-glycerophosphate and or specific PP1 and PP2A inhibitors including microcystin-LR, protein phosphatase 2A inhibitor I (1) or protein phosphatase inhibitor 2 all abrogate H-Ras and K-Ras dependent Raf-1 activation in vitro. |
39(0,1,1,9) | Details |
| 16414982 | Bogatcheva NV, Wang P, Birukova AA, Verin AD, Garcia JG: Mechanism of -induced MAP kinase activation in pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol Physiol. 2006 Jun;290(6):L1139-45. Epub 2006 Jan 13. NaF transiently increases the activity of the MEK kinase known as Raf-1 (approximately 3- to 4-fold increase over basal level), followed by a sustained Raf-1 inhibition (approximately 3- to 4-fold decrease). |
3(0,0,0,3) | Details |
| 12646577 | Tokuda H, Harada A, Hirade K, Matsuno H, Ito H, Kato K, Oiso Y, Kozawa O: Incadronate amplifies -induced vascular endothelial growth factor synthesis in osteoblasts. J Biol Chem. 2003 May 23;278(21):18930-7. Epub 2003 Mar 19. Incadronate markedly enhanced the phosphorylation of Raf-1, MEK1/2, and p44/p42 MAPK induced by PGF2 alpha or 12-O-tetradecanoylphorbol-13- a PKC activator. |
2(0,0,0,2) | Details |