Protein Information

Name leptin
Synonyms LEP; Leptin; Leptin precursor; OB; OBS; Obese protein; Obesity factor; leptin (murine obesity homolog)…

Compound Information

Name sodium fluoride
CAS sodium fluoride (NaF)

Reference List

PubMed Abstract RScore(About this table)
9449624 Mueller WM, Gregoire FM, Stanhope KL, Mobbs CV, Mizuno TM, Warden CH, Stern JS, Havel PJ: Evidence that glucose metabolism regulates leptin secretion from cultured rat adipocytes. Endocrinology. 1998 Feb;139(2):551-8.

Two inhibitors of glycolysis, iodoacetate (0.005-1.0 mM) and sodium fluoride (0.1-5 mM), produced concentration-dependent inhibition of leptin secretion in the presence of 1.6 nM insulin.
89(1,1,1,9) Details
11311219 Evans MJ, Livesey JH, Ellis MJ, Yandle TG: Effect of anticoagulants and storage temperatures on stability of plasma and serum hormones. Clin Biochem. 2001 Mar;34(2):107-12.


DESIGN AND METHODS: Human blood samples were collected from volunteers into EDTA, lithium heparin, sodium fluoride/potassium oxalate, or tubes without anticoagulant, plasma and serum left at -20 degrees C, 4 degrees C or 30 degrees C for 24 and 120 hours then assayed for ACTH, aldosterone, alpha-subunit, AVP, CRH, C-peptide, estradiol, FSH, glucagon, GH, IGF-1, IGFBP-3, insulin, leptin, LH, PPP, PTH, prolactin and VIP, or at room temperature for 0 to 72 hours (BNP, NT-BNP)(n = 6 per condition).
1(0,0,0,1) Details