Protein Information

Name CD11b
Synonyms CD11B; CD11b; CD11b antigen; CR 3 alpha chain; CR3A; Cell surface glycoprotein MAC 1 alpha subunit; ITGAM; Integrin alpha M beta 2…

Compound Information

Name acrylonitrile
CAS 2-propenenitrile

Reference List

PubMed Abstract RScore(About this table)
10397931 Gorbet MB, Yeo EL, Sefton MV: Flow cytometric study of in vitro neutrophil activation by biomaterials. J Biomed Mater Res. 1999 Mar 5;44(3):289-97.

All materials tested [cellophane, an acrylonitrile copolymer (AN69), Pellethane, nylon, polyethylene terephthalate, low density polyethylene, and polydimethylsiloxane] activated isolated human neutrophils, which were resuspended in plasma or serum, to similar extents based on L-selectin shedding, CD11b upregulation, and stimulation of the oxidative burst after 30-min exposure.
32(0,1,1,2) Details
9274839 Sellmayer A, Jeschke C, Fricke H, Schiffl H: Hemodialysis-induced upregulation of granulocyte adhesion molecules CD11b/CD18 is independent from 5-lipoxygenase activity. Nephron. 1997;76(4):418-24.

Dialysis with new cuprophane but not with new acrylonitrile membranes significantly upregulated expression of CD11b and CD18 by 6-fold and 4-fold, respectively.
3(0,0,0,3) Details