Protein Information

Name Acetylcholinesterase
Synonyms ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant…

Compound Information

Name acrylonitrile
CAS 2-propenenitrile

Reference List

PubMed Abstract RScore(About this table)
18675298 Gabrovska K, Marinov I, Godjevargova T, Portaccio M, Lepore M, Grano V, Diano N, Mita DG: The influence of the support nature on the kinetics parameters, inhibition constants and reactivation of immobilized acetylcholinesterase. Int J Biol Macromol. 2008 Nov 1;43(4):339-45. Epub 2008 Jul 15.

Acetylcholinesterase (AChE) was immobilized on two different composite membranes constituted by a chemically modified poly-acrylonitrile (PAN) membrane plus a layer of tethered chitosan of different molecular weight, 10 kDa or 400 kDa.
85(1,1,1,5) Details
6534783 Peter H, Bolt HM: Experimental pharmacokinetics and toxicology of acrylonitrile. . G Ital Med Lav. 1984 May-Jul;6(3-4):77-81.

The effectiveness of N-acetyl-cysteine as an acrylonitrile antidote may be explained by decreased alkylation and inactivation of acetylcholine-esterase.
81(1,1,1,1) Details
7286145 Rajendran S, Muthu M: Effect of acrylonitrile on trehalase, phosphorylase and acetylcholinesterase activities in Tribolium castaneum Herbst and Trogoderma granarium Everts. Experientia. 1981;37(8):886-7.
6(0,0,1,1) Details