Protein Information

Name IL 1 beta
Synonyms Catabolin; IL 1; IL 1 beta; IL 1B; IL1 beta; IL1B; IL1F2; Interleukin 1…

Compound Information

Name acrylonitrile
CAS 2-propenenitrile

Reference List

PubMed Abstract RScore(About this table)
2127434 Laude-Sharp M, Caroff M, Simard L, Pusineri C, Kazatchkine MD, Haeffner-Cavaillon N: Induction of IL-1 during hemodialysis: transmembrane passage of intact endotoxins (LPS). Kidney Int. 1990 Dec;38(6):1089-94.

5(0,0,0,5) Details
2093331 Tetta C, Camussi G, Turello E, Salomone M, Aimo G, Priolo G, Segoloni G, Vercellone A: Production of cytokines in hemodialysis. Blood Purif. 1990;8(6):337-46.


Tumor necrosis factor (TNF-alpha) and interleukin-1 (IL-1 beta) are cytokines primarily produced by monocytes/macrophages when stimulated by endotoxin, complement-derived anaphylatoxins and the specific antigen.
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9096797 Higuchi T, Kuno T, Takahashi S, Kanmatsuse K: Influence of dialysis membranes on interleukin-1 beta and interleukin-1 receptor antagonist production by peripheral blood mononuclear cells. Artif Organs. 1997 Apr;21(4):265-71.

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7530999 Mahiout A, Courtney JM: Effect of dialyser membranes on extracellular and intracellular granulocyte and monocyte activation in ex vivo pyrogen-free conditions. Biomaterials. 1994 Oct;15(12):969-80.

Membrane materials were the unchanged regenerated cellulose, the synthetic polysulphone (PS), a positively charged diethylaminoethyl cellulose (DEAE-C), the negatively charged carboxymethyl cellulose (CMC) and acrylonitrile copolymer (AN).
Investigations were done by release reactions of platelet activating factor (PAF), oxygen radical (O2-), leukotriene B4, prostaglandin E2 (PGE2) and cytokines (IL-1 beta, TNF-alpha, IL-6).
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1726274 Peona C, Fortina A, Colombo P, Filiberti O, Cagna G, Costantini L, Porcu M: [Levels of tumor necrosis factor and interleukin 1 in uremia and in hemodialysis]. Minerva Urol Nefrol. 1991 Jul-Sep;43(3):175-9.

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2702147 Schindler R, Lonnemann G, Shaldon S, Koch KM, Dinarello CA: Induction of interleukin-1 and tumor necrosis factor during in vitro hemodialysis with different membranes. Contrib Nephrol. 1989;74:58-65.

1(0,0,0,1) Details
2702150 Herbelin A, Urena P, Man NK, Drueke T, Descamps-Latscha B: In vitro studies of endotoxin transfer across cellulosic and noncellulosic dialysis membranes. Contrib Nephrol. 1989;74:79-85.


Interleukin-1 production.
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