| Name | aldehyde dehydrogenase (protein family or complex) |
|---|---|
| Synonyms | aldehyde dehydrogenase; aldehyde dehydrogenases |
| Name | carbon disulfide |
|---|---|
| CAS | carbon disulfide |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 6242047 | Schreiner E, Freundt KJ: Behaviour of epoxide hydrolase, glutathione S-transferase, alcohol dehydrogenase, and aldehyde dehydrogenase, respectively, under the influence of carbon disulfide studies with rats in vivo and in vitro. G Ital Med Lav. 1984 May-Jul;6(3-4):131-3. |
7(0,0,1,2) | Details |
| 8861782 | Khan S, Sood C, O'Brien PJ: The involvement of cytochrome P4502E1 in 2-bromoethanol-induced hepatocyte cytotoxicity. Pharmacol Toxicol. 1996 Apr;78(4):241-8. Furthermore, aldehyde dehydrogenase inhibitors-cyanamide or chloral hydrate increased 2-bromoethanol dependent hepatocyte susceptibility. Also, hepatocytes isolated from CYP2E1 induced rats were more susceptible to 2-bromoethanol and hepatocytes isolated from rats pretreated with carbon disulfide to inactivate CYP2E1 were more resistant to 2-bromoethanol treatment. |
1(0,0,0,1) | Details |
| 9072070 | Maccari S, Giglioli W, Semrov E, Fornaciari G: [Collateral effects of disulfiram on the central nervous system in alcoholics that have become totally abstemious. Ann Ital Med Int. 1996 Oct-Dec;11(4):279-83. Disulfiram is used in rehabilitation because it inhibits aldehyde dehydrogenase and consequently causes the disulfiram- reaction (vomiting, vertigo, anxiety, cardiovascular effects) after ingestion of alcoholic beverages. Disulfiram and its metabolite carbon disulfide inhibit dopamine beta-hydroxylase, increasing the levels of and reducing those of in the central nervous system. |
1(0,0,0,1) | Details |