| Name | NF L |
|---|---|
| Synonyms | 68 kDa neurofilament protein; CMT1F; CMT2E; NEFL; NF L; NF68; NFL; Neurofilament light polypeptide… |
| Name | carbon disulfide |
|---|---|
| CAS | carbon disulfide |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17120161 | Song F, Zhao X, Zhou G, Zhu Y, Xie K: Carbon disulfide-induced alterations of neurofilaments and calpains content in rat spinal cord. Neurochem Res. 2006 Dec;31(12):1491-9. Epub 2006 Nov 21. Then, the contents of NF triplet proteins (NF-H, NF-M, NF-L) and two calpain isoforms (m-calpain and mu-calpain) in both fractions were determined by immunoblotting. |
4(0,0,0,4) | Details |
| 9007038 | Valentine WM, Amarnath V, Graham DG, Morgan DL, Sills RC: CS2-mediated cross-linking of erythrocyte spectrin and neurofilament protein: dose response and temporal relationship to the formation of axonal swellings. Toxicol Appl Pharmacol. 1997 Jan;142(1):95-105. |
3(0,0,0,3) | Details |
| 19165470 | Song F, Zhang C, Wang Q, Zeng T, Xie K: Alterations in neurofilaments content and calpains activity of sciatic nerve of carbon disulfide-treated rats. Arch Toxicol. 2009 Jun;83(6):587-94. Epub 2009 Jan 23. The contents of neurofilament triplet proteins (NF-H, NF-M, NF-L) and two calpain isoforms (m-calpain and u-calpain) in sciatic nerves were determined by immunoblotting. |
3(0,0,0,3) | Details |
| 10669001 | Sills RC, Valentine WM, Moser V, Graham DG, Morgan DL: Characterization of carbon disulfide neurotoxicity in C57BL6 mice: behavioral, morphologic, and molecular effects. Toxicol Pathol. 2000 Jan-Feb;28(1):142-8. Electron microscopic examination revealed swollen axons with massive accumulation of neurofilament proteins within the axoplasm. |
2(0,0,0,2) | Details |
| 9585486 | Erve JC, Amarnath V, Graham DG, Sills RC, Morgan AL, Valentine WM: Carbon disulfide and N,N-diethyldithiocarbamate generate thiourea cross-links on erythrocyte spectrin in vivo. Chem Res Toxicol. 1998 May;11(5):544-9. This observation supports the utility of cross-linking of peripheral proteins as a specific dosimeter of internal exposure for CS2 and provides a mechanistic explanation to account for the high-molecular-weight neurofilament protein species isolated from rats exposed to CS2 or N, N-diethyldithiocarbamate. |
1(0,0,0,1) | Details |
| 16474999 | Song F, Yu S, Zhao X, Zhang C, Xie K: Carbon disulfide-induced changes in cytoskeleton protein content of rat cerebral cortex. Neurochem Res. 2006 Jan;31(1):71-9. Then, the contents of six cytoskeletal protein (NF-L, NF-M, NF-H, alpha-tubulin, beta-tubulin, and beta-actin) in both fractions were determined by immunoblotting. |
1(0,0,0,1) | Details |
| 857582 | Savolainen H, Lehtonen E, Vainio H: CS2 binding to rat spinal neurofilaments. Acta Neuropathol. 1977 Mar 31;37(3):219-23. The present data may indicate that the high binding of CS2 to the neurofilament protein contributes to the increase in neurofilaments in chronic CS2 intoxication. |
1(0,0,0,1) | Details |
| 16002115 | Sills RC, Harry GJ, Valentine WM, Morgan DL: Interdisciplinary neurotoxicity inhalation studies: carbon disulfide and carbonyl sulfide research in F344 rats. Toxicol Appl Pharmacol. 2005 Sep 1;207(2 Suppl):245-50. The observation of dose-dependent covalent cross-linking in neurofilament proteins prior to the onset of lesions is consistent with this process contributing to the development of the neurofilamentous axonal swellings characteristic of carbon disulfide neurotoxicity. |
6(0,0,1,1) | Details |