Name | glutathione S transferase alpha 1 |
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Synonyms | GST class alpha 1; Gst2; GST class alpha; GST class alpha member 1; GST epsilon; GSTA 1; GSTA1; GSTA1 protein… |
Name | carbon disulfide |
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CAS | carbon disulfide |
PubMed | Abstract | RScore(About this table) | |
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18784548 | Jonsson LS, Littorin M, Axmon A, Jonsson BA, Broberg K: Lung function in relation to 2-thiothiazolidine-4-carboxylic acid and genetic effect modification among rubber workers in Sweden. J Occup Environ Med. 2008 Sep;50(9):1006-12. Levels of 2-thiothiazolidine-4-carboxylic acid (a marker of carbon disulfide and vulcanization fumes) was assessed with liquid chromatography tandem mass spectrometry. The association was modified by glutathione S-transferase alpha 1 (GSTA1)-52 and GSTP1-114. |
1(0,0,0,1) | Details |
17333241 | Jonsson LS, Broberg K, Bergendorf U, Axmon A, Littorin M, Jonsson BA: Levels of 2-thiothiazolidine-4-carboxylic acid (TTCA) and effect modification of polymorphisms of -related genes in vulcanization workers in the southern Sweden rubber industries. Int Arch Occup Environ Health. 2007 Jul;80(7):589-98. Epub 2007 Feb 28. One of the toxic compounds in the industry is carbon disulfide (CS (2)), which is biotransformed to 2-thiothiazolidine-4-carboxylic acid (TTCA). Genotyping of the single nucleotide polymorphisms GCLC-129, GCLM-588, GSTA1-52, GSTP1-105 and GSTP1-114 and deletions of GSTM1 and GSTT1 were performed with real-time PCR or ordinary PCR and subsequent agarose electrophoresis. |
1(0,0,0,1) | Details |