| 15792633 |
Haritos VS, Dojchinov G: Carbonic anhydrase metabolism is a key factor in the toxicity of CO2 and COS but not CS2 toward the flour beetle Tribolium castaneum [Coleoptera: Tenebrionidae]. Comp Biochem Physiol C Toxicol Pharmacol. 2005 Jan;140(1):139-47.
The analogues carbon dioxide (CO (2)), carbonyl sulfide (COS) and carbon disulfide (CS (2)) have been useful as substrate probes for enzyme activities.
We also investigated the role of carbonic anhydrases in CO (2), COS and CS (2) toxicity using a specific inhibitor, acetazolamide, administered to Tribolium castaneum (Herbst) larvae via the diet. |
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