Name | endothelial nitric oxide synthase |
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Synonyms | Constitutive NOS; NOS 3; NOS3; EC NOS; ECNOS; ENOS; Endothelial NOS; Endothelial nitric oxidase synthase… |
Name | carbon tetrachloride |
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CAS | tetrachloromethane |
PubMed | Abstract | RScore(About this table) | |
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19527736 | Cho YK, Yun JW, Park JH, Kim HJ, Park DI, Sohn CI, Jeon WK, Kim BI, Jin W, Kwon YH, Shin MK, Yoo TM, Kang JH, Park CS: Deleterious effects of silymarin on the expression of genes controlling endothelial nitric oxide synthase activity in carbon tetrachloride-treated rat livers. Life Sci. 2009 Aug 12;85(7-8):281-90. Epub 2009 Jun 13. |
6(0,0,1,1) | Details |
19628654 | Theodorakis NG, Wang YN, Wu JM, Maluccio MA, Sitzmann JV, Skill NJ: Role of endothelial nitric oxide synthase in the development of portal hypertension in the carbon tetrachloride induced liver fibrosis model. Am J Physiol Gastrointest Liver Physiol. 2009 Jul 23. |
6(0,0,1,1) | Details |
18070013 | Zhang ZQ, Qiu JF, Luo M, Sun YW, Zhao G, Chen W, Liu H, Wu ZY: Liposome-mediated gene transfer of endothelial nitric oxide synthase to cirrhotic rat liver decreases intrahepatic vascular resistance. J Gastroenterol Hepatol. 2008 Aug;23(8 Pt 2):e487-93. Epub 2007 Dec 7. METHODS: Hepatic cirrhosis was induced in male Sprague-Dawley rats by intraperitoneal injection of carbon tetrachloride (CCl (4)), whereas the control normal rats were given the same dose of peanut oil. |
2(0,0,0,2) | Details |
18429990 | Leung TM, Tipoe GL, Liong EC, Lau TY, Fung ML, Nanji AA: Endothelial nitric oxide synthase is a critical factor in experimental liver fibrosis. Int J Exp Pathol. 2008 Aug;89(4):241-50. Epub 2008 Apr 21. Chronic liver injury was induced by administration of carbon tetrachloride (CCl (4)) to mice for 8 weeks. 5-Methylisothiourea hemisulphate (SMT), an iNOS inhibitor, or a NOS substrate were injected subcutaneously. |
2(0,0,0,2) | Details |
18412020 | Knorr A, Hirth-Dietrich C, Alonso-Alija C, Harter M, Hahn M, Keim Y, Wunder F, Stasch JP: activation of soluble guanylate cyclase by BAY 60-2770 in experimental liver fibrosis. Arzneimittelforschung. 2008;58(2):71-80. However, production is downregulated in the cirrhotic liver due to the reduced activity of the endothelial nitric oxide synthase. METHODS: The compound was studied in the pig serum model and the carbon tetrachloride model. |
-independent 1(0,0,0,1) | Details |
16698588 | Yuan GJ, Gong ZJ, Sun XM, Zheng SH, Li X: Tea polyphenols inhibit expressions of iNOS and TNF-alpha and prevent lipopolysaccharide-induced liver injury in rats. Hepatobiliary Pancreat Dis Int. 2006 May;5(2):262-7. BACKGROUND: Tea polyphenols have been shown to protect against carbon tetrachloride (CCl4)-induced liver injury, liver fibrosis, hepatic ischemia-reperfusion injury. Inducible synthase (iNOS) protein and TNF-alpha, iNOS and endothelial nitric oxide synthase (eNOS) mRNA expressions in the liver were detected by immunohistochemistry and reverse transcriptase-polymerase chain reaction (RT-PCR), respectively. |
1(0,0,0,1) | Details |
19401196 | Zhang ZQ, Shi B, Wu GQ, Qin KR, Jiang ZL, Zhu L: Combined use of nifedipine offers better effects on portal vein nonuniform remodeling in carbon tetrachloride (CCl (4))-induced portal hypertensive rats. Eur J Pharmacol. 2009 Jun 24;613(1-3):108-13. Epub 2009 May 3. |
and 0(0,0,0,0) | Details |
18317400 | Liu H, Subramony C, Nowicki M: Posttranslational activation of endothelial nitric oxide synthase attenuates carbon tetrachloride-induced hepatotoxicity in newborn rats. Pediatr Res. 2008 Jun;63(6):613-9. |
81(1,1,1,1) | Details |