Protein Information

Name Fas Ligand
Synonyms APT1LG1; FAS; APTL; Apoptosis (APO 1) antigen ligand 1; Apoptosis antigen ligand; Apoptosis antigen ligand 1; CD178; CD178 antigen…

Compound Information

Name carbon tetrachloride
CAS tetrachloromethane

Reference List

PubMed Abstract RScore(About this table)
16212920 Pan H, Hong F, Radaeva S, Gao B: Hydrodynamic gene delivery of interleukin-22 protects the mouse liver from concanavalin A-, carbon tetrachloride-, and Fas ligand-induced injury via activation of STAT3. Cell Mol Immunol. 2004 Feb;1(1):43-9.
31(0,1,1,1) Details
16831245 Wen T, Ren F, Liu Y, Wu ZM, Zhao JY: [Expression of Fas antigen and Fas ligand in acute liver injury induced by carbon tetrachloride in rat]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2006 Jul;18(7):417-20.
12(0,0,2,2) Details
18291569 Lee KJ, Choi JH, Kim HG, Han EH, Hwang YP, Lee YC, Chung YC, Jeong HG: Protective effect of saponins derived from the roots of Platycodon grandiflorum against carbon tetrachloride induced hepatotoxicity in mice. Food Chem Toxicol. 2008 May;46(5):1778-85. Epub 2008 Jan 18.

To determine whether Fas/Fas ligand (FasL) pathway involved in CCl (4)-induced acute liver injury, Fas and FasL proteins and caspase-3, -8 activities were tested by western blotting and ELISA.
1(0,0,0,1) Details
16609999 Zhang LJ, Zheng WD, Shi MN, Wang XZ: Effects of interleukin-10 on activation and apoptosis of hepatic stellate cells in fibrotic rat liver. World J Gastroenterol. 2006 Mar 28;12(12):1918-23.

AIM: To study the effects of interleukin-10 (IL-10) on the expression of alpha-smooth muscle actin (alpha-SMA), nuclear factor- kappa B (NF- kappa B) and Fas/Fas ligand (FasL) in hepatic stellate cells of experimental rats with hepatic fibrosis.
Fibrotic group was injected intraperitoneally with 50% carbon tetrachloride (CCl (4)) (2 mL/kg), twice a week.
1(0,0,0,1) Details
18436364 Lee KJ, Choi JH, Khanal T, Hwang YP, Chung YC, Jeong HG: Protective effect of caffeic acid phenethyl ester against carbon tetrachloride-induced hepatotoxicity in mice. Toxicology. 2008 Jun 3;248(1):18-24. Epub 2008 Mar 20.

To determine whether the Fas/Fas ligand (FasL) pathway is involved in CCl (4)-induced acute liver injury, Fas and FasL proteins and caspase-3 and -8 activities were tested by western blotting and ELISA.
1(0,0,0,1) Details