| Name | cytochrome c |
|---|---|
| Synonyms | CYC; CYCS; Cytochrome C; HCS; Cytochrome Cs |
| Name | carbon tetrachloride |
|---|---|
| CAS | tetrachloromethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19595748 | Chan WH, Liao JW, Chou CP, Chan PK, Wei CF, Ueng TH: Induction of CYP1A1, 2B, 2E1 and 3A in rat liver by organochlorine pesticide dicofol. Toxicol Lett. 2009 Oct 28;190(2):150-5. Epub 2009 Jul 10. Treatments with 10 and 25mg/kg dicofol produced dose-related increases of cytochrome P450 and cytochrome b (5) contents and -cytochrome c reductase, 7-ethoxyresorufin O-deethylase, pentoxyresorufin O-dealkylase, hydroxylase, and erythromycin N-demethylase activities in liver microsomes. |
1(0,0,0,1) | Details |
| 19072832 | Aram G, Potter JJ, Liu X, Wang L, Torbenson MS, Mezey E: Deficiency of reduced form oxidase enhances hepatocellular injury but attenuates fibrosis after chronic carbon tetrachloride administration. Hepatology. 2009 Mar;49(3):911-9. |
0(0,0,0,0) | Details |
| 16393475 | Lee SJ, Oh PS, Ko JH, Lim K, Lim KT: Protective effect of glycoprotein isolated from Ulmus davidiana Nakai on carbon tetrachloride-induced mouse liver injury. J Pharm Pharmacol. 2006 Jan;58(1):143-52. We evaluated lipid peroxidation in / oxidase (G/GO)-induced BNL CL.2 cells and measured thiobarbituric acid reactive substances (TBARS), lactate dehydrogenase (LDH), (NO), antioxidant enzyme (superoxide dismutase (SOD), catalase (CAT) and peroxidase (GPx)), activity of cytotoxic-related signals (hepatic cytochrome c, nuclear factor-kappa B (NF-kappaB) and activator protein-1 (AP-1)) and levels of plasma lipids (triglyceride (TG) and total (TC)) in carbon tetrachloride (CCl (4,) 1.0 mL kg (-1))-induced A/J mouse. |
6(0,0,1,1) | Details |
| 16640835 | Lee TY, Chang HH, Wang GJ, Chiu JH, Yang YY, Lin HC: -soluble extract of Salvia miltiorrhiza ameliorates carbon tetrachloride-mediated hepatic apoptosis in rats. J Pharm Pharmacol. 2006 May;58(5):659-65. Hepatic cytosolic Bax, Bcl-2, cytochrome c, and calpain-mu expressions were measured by Western blot analysis. |
3(0,0,0,3) | Details |
| 16038630 | Cai Y, Gong LK, Qi XM, Li XH, Ren J: Apoptosis initiated by carbon tetrachloride in mitochondria of rat primary cultured hepatocytes. Acta Pharmacol Sin. 2005 Aug;26(8):969-75. The release of cytochrome c and Bcl-X (L) was detected by Western blot. |
2(0,0,0,2) | Details |
| 17292878 | Park EJ, Zhao YZ, Kim YC, Sohn DH: Bakuchiol-induced caspase-3-dependent apoptosis occurs through c-Jun NH2-terminal kinase-mediated mitochondrial translocation of Bax in rat liver myofibroblasts. Eur J Pharmacol. 2007 Mar 22;559(2-3):115-23. Epub 2007 Jan 23. Bakuchiol, a prenylated phenolic terpene isolated from the seed of Psoralea corylifolia L. (Leguminosae), reduced activated hepatic stellate cells when treated to rats during liver injury recovery period as demonstrated by alpha-smooth muscle actin immunostaining in rat liver and induced apoptosis in activated hepatic stellate cells/myofibroblasts as demonstrated by DNA fragmentation, activation of caspase-3, release of cytochrome c into the cytoplasm, translocation of Bax into mitochondria, and the proteolytic cleavage of poly (ADP- polymerase (PARP) in vitro. |
2(0,0,0,2) | Details |
| 17541162 | Chiu PY, Leung HY, Siu AH, Poon MK, Ko KM: Schisandrin B decreases the sensitivity of mitochondria to -induced permeability transition and protects against carbon tetrachloride toxicity in mouse livers. Biol Pharm Bull. 2007 Jun;30(6):1108-12. The enhanced sensitivity to mitochondrial PT was associated with increases in mitochondrial Ca2+ content as well as the extent of reactive oxidant species (ROS) production and cytochrome c release. |
2(0,0,0,2) | Details |
| 19637241 | Sakai T, Liu L, Teng X, Ishimaru N, Mukai-Sakai R, Tran NH, Kim SM, Sano N, Hayashi Y, Kaji R, Fukui K: Inflammatory disease and cancer with a decrease in Kupffer cell numbers in Nucling-knockout mice. Int J Cancer. 2010 Mar 1;126(5):1079-94. The cytochrome c-triggered formation of apoptosomes represents a key-initiating event in apoptosis. |
1(0,0,0,1) | Details |
| 18160022 | Chiu PY, Leung HY, Siu AH, Chen N, Poon MK, Ko KM: Long-term treatment with a Yang-invigorating Chinese herbal formula produces generalized tissue protection against oxidative damage in rats. Rejuvenation Res. 2008 Feb;11(1):43-62. This was evidenced by decreases in the sensitivity of mitochondria to Ca2+-induced permeability transition, and in the levels of mitochondrial malondialdehyde production, Ca2+ loading, and cytochrome c release in the tissues examined. |
1(0,0,0,1) | Details |
| 15022168 | Beissenhirtz MK, Kwan RC, Ko KM, Renneberg R, Scheller FW, Lisdat F: Comparing an in vitro electrochemical measurement of scavenging activity with an in vivo assessment of antioxidant potential in Chinese tonifying herbs. Phytother Res. 2004 Feb;18(2):149-53. The in vitro scavenging activity (as determined by electrochemical measurement) and the in vivo antioxidant potential (as determined by a mouse model of carbon tetrachloride (CCl (4)) hepatotoxicity) of methanolic extracts prepared from 10 Chinese tonifying herbs were compared. Electrochemical measurement using a cytochrome c (Cyt. c) sensor showed that all of the tested herbal extracts exhibited a medium scavenging activity of different potency, as indicated by their IC (50) values. |
1(0,0,0,1) | Details |
| 17432597 | Shiriaeva AP, Baidiuk EV, Arkad'eva AV, Okovityi SV, Morozov VI, Sakuta GA: [Hepatocyte mitochondrion respiratory chain in rats with experimental toxic hepatitis]. Tsitologiia. 2007;49(2):125-32. Alterations of SCCR, -cytochrome c-reductase, cytochrome c oxidase and ATP-synthase activities have an adaptive nature to compensate for impaired NCCR function. |
1(0,0,0,1) | Details |
| 17002669 | Lee SJ, Oh PS, Lim KT: Hepatoprotective and hypolipidaemic effects of glycoprotein isolated from Gardenia jasminoides ellis in mice. Clin Exp Pharmacol Physiol. 2006 Oct;33(10):925-33. In addition, in these mice GJE resulted in increased production and the activation of anti-oxidant enzymes, accompanied by the inhibition of the cytotoxic-related signals hepatic cytochrome c, nuclear factor-kappaB and activator protein-1. |
1(0,0,0,1) | Details |
| 17466404 | Anselmi K, Stolz DB, Nalesnik M, Watkins SC, Kamath R, Gandhi CR: Gliotoxin causes apoptosis and necrosis of rat Kupffer cells in vitro and in vivo in the absence of oxidative stress: exacerbation by caspase and serine protease inhibition. J Hepatol. 2007 Jul;47(1):103-13. Epub 2007 Apr 5. This effect was associated with mitochondrial cytochrome c release, caspase-3 activation and ATP depletion. |
1(0,0,0,1) | Details |