Protein Information

Name cholinesterase
Synonyms Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase…

Compound Information

Name dimefox
CAS

Reference List

PubMed Abstract RScore(About this table)
13889182 EDERY H: Effects of organophosphorous compounds, oximes and atropine injected into the third ventricle of unanaesthetized dogs. Br J Pharmacol Chemother. 1962 Feb;18:19-28.

The injection of 40 to 80 mg of dimefox and of 50 mg of schradan elicited involuntary micturition, vomiting, salivation and defaecation.
This view is supported by the finding of reduced blood cholinesterase activity.
1(0,0,0,1) Details
13403872 FENWICK ML, BARRON JR, WATSON WA: The conversion of dimefox into an anticholinesterase by rat liver in vitro. Biochem J. 1957 Jan;65(1):58-67.
81(1,1,1,1) Details
7170026 Lehotzky K: Effect of pesticides on central and peripheral nervous system function in rats. Neurobehav Toxicol Teratol. 1982 Nov-Dec;4(6):665-9.

The neurobehavioral toxicity of three organophosphate pesticides, sumithion, dimefox and trichlorphon, was evaluated in rats using measures of open field activity, rotorod performance, conditioned escape from shock, and nerve conduction velocity.
These measures were correlated with blood and brain cholinesterase level determinations.
2(0,0,0,2) Details