Protein Information

Name Toll like receptor 4
Synonyms CD284; CD284 antigen; TLR 4; TLR4; TOLL; Toll like receptor 4; Toll like receptor 4 precursor; hToll…

Compound Information

Name carbon tetrachloride
CAS tetrachloromethane

Reference List

PubMed Abstract RScore(About this table)
17504260 Hua J, Qiu de K, Li JQ, Li EL, Chen XY, Peng YS: Expression of Toll-like receptor 4 in rat liver during the course of carbon tetrachloride-induced liver injury. J Gastroenterol Hepatol. 2007 Jun;22(6):862-9. Epub 2007 May 17.
17(0,0,2,7) Details
15259507 Su GL, Wang SC, Aminlari A, Tipoe GL, Steinstraesser L, Nanji A: Impaired hepatocyte regeneration in toll-like receptor 4 mutant mice. Dig Dis Sci. 2004 May;49(5):843-9.

In these experiments, we sought to determine the role of toll-like receptor 4 in acute liver injury by carbon tetrachloride by utilizing the naturally occurring toll-like receptor 4 mutant and wild-type mice strains.
9(0,0,1,4) Details
18824281 Fang HL, Lai JT, Lin WC: Inhibitory effect of olive oil on fibrosis induced by carbon tetrachloride in rat liver. Clin Nutr. 2008 Dec;27(6):900-7. Epub 2008 Sep 27.

RESULTS: RT-PCR analysis showed that CCl (4) increased the hepatic mRNA expressions of lipopolysaccharide binding protein, CD14, Toll-like receptor-4, NADPH oxidase, nuclear factor-kappa beta, collagen (alpha1) (I), collagen (alpha1) (III), and transforming growth factor beta1.
1(0,0,0,1) Details