| Name | Yb 1 |
|---|---|
| Synonyms | BP 8; CBF A; CCAAT binding transcription factor I subunit A; CSDA 2; CSDA2; CSDB; DBPB; DNA binding protein B… |
| Name | carbon tetrachloride |
|---|---|
| CAS | tetrachloromethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16012952 | Inagaki Y, Kushida M, Higashi K, Itoh J, Higashiyama R, Hong YY, Kawada N, Namikawa K, Kiyama H, Bou-Gharios G, Watanabe T, Okazaki I, Ikeda K: Cell type-specific intervention of transforming growth factor beta/Smad signaling suppresses collagen gene expression and hepatic fibrosis in mice. Gastroenterology. 2005 Jul;129(1):259-68. Adenovirus-mediated YB-1 expression under the control of the COL1A2 enhancer significantly decreased COL1A2 promoter activity after carbon tetrachloride injection and subsequently suppressed the progression of hepatic fibrosis. |
38(0,1,2,3) | Details |
| 16278212 | Dooley S, Said HM, Gressner AM, Floege J, En-Nia A, Mertens PR: Y-box protein-1 is the crucial mediator of antifibrotic interferon-gamma effects. J Biol Chem. 2006 Jan 20;281(3):1784-95. Epub 2005 Nov 8. Here, we report that YB-1 activation via the Jak1 signaling pathway is required and sufficient to confer interferon-gamma-dependent activation of the smad7 gene. |
3(0,0,0,3) | Details |
| 20141739 | Shen DZ, Tao Q, DU JX, Ding SD, Chen GF, Hu YY, Liu P: [Effects of Yiguanjian Decoction on liver cirrhosis formation:a differential proteomics study in rats.]. Zhong Xi Yi Jie He Xue Bao. 2010 Feb;8(2):158-67. Rat cirrhosis model was established by intraperitoneal injection of 50% carbon tetrachloride (CCl4) plus olive oil solution (1 mL/kg, twice weekly for 9 weeks). In all 50 protein spots identified by MALDI-TOF/TOF-MS and database querying, there were 5 protein spots related to oxidative stress named Cu/Zn SOD, DJ-1, glutathione synthetase, glutathione S-transferase Yb-1 subunit and aldo-keto reductase family 7, A2 respectively. |
3(0,0,0,3) | Details |