| Name | CCL4 |
|---|---|
| Synonyms | ACT2; Lag1; SCYA 2; SCYA2; AT744.1; Act2; CCL4; G 26… |
| Name | carbon tetrachloride |
|---|---|
| CAS | tetrachloromethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 20302068 | Jiang YH, Gao SQ, Li ZL, Cao B, Li ZW: [Analysis of spectral intensity of fermi resonance of molecules] . Guang Pu Xue Yu Guang Pu Fen Xi. 2010 Jan;30(1):6-8. The rule about Fermi resonance was obtained from the Raman spectra of carbon disulfide (CS) and carbon tetrachloride (CCL4): (1) The energy can transfer between a fundamental and an overtone frequency about Fermi resonance; the two spectra have the same intensity. |
31(0,1,1,1) | Details |
| 18468249 | Yuasa T, Yamamoto T, Rivas-Carrillo JD, Chen Y, Navarro-Alvarez N, Soto-Guiterrez A, Noguchi H, Matsumoto S, Tanaka N, Kobayashi N: Laparoscopy-assisted creation of a liver failure model in pigs. Cell Transplant. 2008;17(1-2):187-93. In our model, all of three hepatic arteries were resected, 5, 7.5, or 10 ml of carbon tetrachloride (CCL4) was injected into the liver through the portal vein, and subsequently the portal vein was mechanically occluded for 30 min. |
9(0,0,1,4) | Details |
| 17522070 | Zidek N, Hellmann J, Kramer PJ, Hewitt PG: Acute hepatotoxicity: a predictive model based on focused illumina microarrays. Toxicol Sci. 2007 Sep;99(1):289-302. Epub 2007 May 22. Low and high doses of tetracycline, carbon tetrachloride (CCL4), 1-naphthylisothiocyanate (ANIT), erythromycin estolate, (AAP), or chloroform as hepatotoxicants, clofibrate, naloxone, quinidine, or dexamethasone as nonhepatotoxic compounds, were administered as a single dose to male Sprague-Dawley rats. |
7(0,0,1,2) | Details |
| 16997622 | Xia F, He Z, Li K, Wang X, Dong J: Evaluation of the role of sympathetic denervation on hepatic function. . Hepatol Res. 2006 Dec;36(4):259-64. Epub 2006 Sep 25. Eighty healthy male Wistar rats were divided randomly into four groups: Sham group, carbon tetrachloride group (CCL4), group (6-OHDA), and CCL4+6-OHDA group. |
7(0,0,1,2) | Details |
| 16810750 | Tang XP, Zhang M, Yang X, Chen LM, Zeng Y: Differentiation of human umbilical cord blood stem cells into hepatocytes in vivo and in vitro. World J Gastroenterol. 2006 Jul 7;12(25):4014-9. In the animal experiments, the survival SD rats with acute hepatic injury after carbon tetrachloride (CCL4) injection 48 h were randomly divided into three groups. |
6(0,0,1,1) | Details |
| 16374873 | Quintana-Bustamante O, Alvarez-Barrientos A, Kofman AV, Fabregat I, Bueren JA, Theise ND, Segovia JC: Hematopoietic mobilization in mice increases the presence of bone marrow-derived hepatocytes via in vivo cell fusion. Hepatology. 2006 Jan;43(1):108-16. Recurrent liver injury in mice expressing green fluorescent protein (EGFP) in all hematopoietic-derived cells was produced by 3 months of carbon tetrachloride (CCL4) injections. |
6(0,0,1,1) | Details |
| 19424597 | Huang Q, Xie Q, Shi CC, Xiang XG, Lin LY, Gong BD, Zhao GD, Wang H, Jia NN: Expression of angiotensin-converting enzyme 2 in CCL4-induced rat liver fibrosis. Int J Mol Med. 2009 Jun;23(6):717-23. |
3(0,0,0,3) | Details |
| 17392098 | Bai X, Qiu A, Guan J, Shi Z: Antioxidant and protective effect of an oleanolic acid-enriched extract of A. deliciosa root on carbon tetrachloride induced rat liver injury. Asia Pac J Clin Nutr. 2007;16 Suppl 1:169-73. The antioxidant and hepatoprotective activities of various EEAD fractions and OLA were carefully investigated by the methods of ferric (FTC) and thiobarbituric acid (TBA), as well as the model of CCL4-induced liver toxicity in rats. |
3(0,0,0,3) | Details |
| 18664124 | Bezborodkina NN, Okovityi SV, Kudriavtseva MV, Kirik OV, Zarubina IV, Kudriavtsev BN: [Morphometry of hepatocyte mitochondrial apparatus in normal and cirrhotic rat liver]. Tsitologiia. 2008;50(3):228-36. Morphometric electron microscopy study of the hepatocyte mitochondrial apparatus and morphofunctional analysis of the degree of pathological alterations were carried out on the liver of rats with CCL4-cirrhosis (experimental group). |
2(0,0,0,2) | Details |
| 16718785 | Nie QH, Zhang YF, Xie YM, Luo XD, Shao B, Li J, Zhou YX: Correlation between TIMP-1 expression and liver fibrosis in two rat liver fibrosis models. World J Gastroenterol. 2006 May 21;12(19):3044-9. AIM: To evaluate serum TIMP-1 level and the correlation between TIMP-1 expression and liver fibrosis in immune-induced and CCL4-induced liver fibrosis models in rats. |
2(0,0,0,2) | Details |
| 15761983 | Zhang Q, Zhao Y, Zhang DB, Sun LJ: Effect of Sinai san decoction on the development of non-alcoholic steatohepatitis in rats. World J Gastroenterol. 2005 Mar 7;11(9):1392-5. AIM: To explore the effect of Sinai san decoction on the development of non-alcoholic steatohepatitis induced by CCL4 combined with a fat-rich diet in rats. |
2(0,0,0,2) | Details |
| 17828713 | Reyes-Gordillo K, Muriel P, Castaneda-Hernandez G, Favari L: Pharmacokinetics of diclofenac in rats intoxicated with CCL4, and in the regenerating liver. Biopharm Drug Dispos. 2007 Nov;28(8):415-22. |
1(0,0,0,1) | Details |
| 17686161 | Zhang L, Duan YY, Yin JK, Cui JH, Zhang Y, Cao TS: Grey scale enhancement by a new self-made contrast agent in early cirrhotic stage of rabbit liver. BMC Gastroenterol. 2007 Aug 8;7:32. METHODS: We constructed experimental models of hepatic fibrosis involving five stages from F0 to F4 via administration of CCL4 (0.01 ml/kg BW) every 3 days for 3 months. |
1(0,0,0,1) | Details |
| 17721639 | Abdel-Salam OM, Sleem AA, Morsy FA: Effects of biphenyldimethyl-dicarboxylate administration alone or combined with silymarin in the CCL4 model of liver fibrosis in rats. ScientificWorldJournal. 2007 Aug 24;7:1242-55. The effect of biphenyldimethyldicarboxylate (DDB), a synthetic compound, in use for the treatment of chronic hepatitis was studied on hepatic injury caused in rats by administration of carbon tetrachloride (CCl4). |
1(0,0,0,1) | Details |
| 19783517 | Anandan R, Jayakar B, Karar B, Babuji S, Manavalan R, Kumar RS: Effect of extract of flowers of Vitex trifolia Linn. on CCL4 induced hepatic injury in rats. Pak J Pharm Sci. 2009 Oct;22(4):391-4. |
1(0,0,0,1) | Details |
| 16705248 | Topuria D, Didava G, Lobdjanidze N, Sujashvili L: Treatment of toxic liver damage by antihepatocytotoxic serum. Georgian Med News. 2006 Apr;(133):116-9. In I and II groups we were modelling acute liver failure by injections of hepatotoxic agent CCL4 (I) and performing 70% hepatectomy (II), III group was served as control group, and IV group served as donors for HPCs. |
1(0,0,0,1) | Details |
| 16382155 | Ju W, Ogawa A, Heyer J, Nierhof D, Yu L, Kucherlapati R, Shafritz DA, Bottinger EP: Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation. Mol Cell Biol. 2006 Jan;26(2):654-67. However, necrogenic CCL4-induced hepatocyte proliferation was significantly increased in S2HeKO compared to Ctrl and S3KO livers, and transplanted S2HeKO hepatocytes repopulated recipient liver at dramatically increased rates compared to Ctrl hepatocytes in vivo. |
1(0,0,0,1) | Details |
| 16636395 | Kurdadze E, Lobdjanidze N, Sujashvili L, Topuria D, Shanava K: Toxic acute liver failure treatment by isolated hepatocytes allotransplantation in experimental. Georgian Med News. 2006 Mar;(132):105-8. We provide experiments on 45 white laboratory Vistar line rats (150-200gr) which were kept on standard environment, animals were divided into three equal groups: I group (n=20) was served as a control group, in which we provide acute liver failure modelling, by toxic agent (carbontetrachloride CCL4 ) treatment by naso-gastric tube, After acute liver failure modelling, in the II group (n=20) of animals we were conducting liver cell transplantation, III group (n=5) animals were served as donors for isolated hepatocyte uptake. |
1(0,0,0,1) | Details |
| 17984565 | Antelava NA, Gogoluari MI, Gogoluari LI, Pirtskhalaishvili NN, Okudzhava MV: [Efficacy and safety of heptral, vitamin B6 and during toxic hepatitis induced by CCL4]. Georgian Med News. 2007 Sep;(150):53-6. |
1(0,0,0,1) | Details |
| 19761043 | Meera R, Devi P, Kameswari B, Madhumitha B, Merlin NJ: Antioxidant and hepatoprotective activities of Ocimum basilicum Linn. and Trigonella foenum-graecum Linn. against H2O2 and CCL4 induced hepatotoxicity in goat liver. Indian J Exp Biol. 2009 Jul;47(7):584-90. |
1(0,0,0,1) | Details |
| 16757302 | Nardo B, Puviani L, Caraceni P, Pacile V, Bertelli R, Beltempo P, Cavallari G, Chieco P, Pariali M, Pertosa AM, Angiolini G, Domenicali M, Neri F, Tsivian M, Bernardi M, Cavallari A: Successful treatment of CCL4-induced acute liver failure with portal vein arterialization in the rat. Transplant Proc. 2006 May;38(4):1187-9. |
1(0,0,0,1) | Details |
| 17127519 | Al-Waili NS, Saloom KY, Al-Waili TN, Al-Waili AN, Akmal M, Al-Waili FS, Al-Waili HN: Influence of various diet regimens on deterioration of hepatic function and hematological parameters following carbon tetrachloride: a potential protective role of natural honey. Nat Prod Res. 2006 Nov;20(13):1258-64. Rats in all the groups were i.m. administered CCL4 (2.4 mL kg b. wt.-1). |
1(0,0,0,1) | Details |
| 16510928 | Topuria D, Kakabadze Z, Lobdjanidze N, Chavchanidze N: Anti-hepato-cytotoxic serum treatment results in acute liver failure. . Georgian Med News. 2006 Jan;(130):111-5. The aim of the study was the evaluation of the clinical course and complications of acute liver failure in experiment, We created an experimental model using hepatotoxic substance (CCL4), which causes centrilobular lesions in liver parenchyma. |
1(0,0,0,1) | Details |
| 16941689 | Guarner C, Gonzalez-Navajas JM, Sanchez E, Soriando G, Frances R, Chiva M, Zapater P, Benlloch S, Munoz C, Pascual S, Balanzo J, Perez-Mateo M, Such J: The detection of bacterial DNA in blood of rats with CCl4-induced cirrhosis with ascites represents episodes of bacterial translocation. Hepatology. 2006 Sep;44(3):633-9. Cirrhosis was induced in rats by ingestion of CCL4. |
1(0,0,0,1) | Details |
| 16898077 | Kotsiou A, Tsamouri M, Anagnostopoulou S, Tzivras M, Vairactaris E, Tesseromatis C: H3 serum levels following lidocaine administration in rats with CCL4 induced liver damage. Eur J Drug Metab Pharmacokinet. 2006 Apr-Jun;31(2):97-101. The influence of lidocaine on serum, heart and liver levels in Wistar rats after liver injury induced by carbon tetrachloride CCl4 0.4 ml/kg x 2/wkl, was investigated. 40 male Wistar rats were divided into four groups (I, II, III, IV; n=10), Group I animals received only (labelled + cold substance) 40 mg/kg/12 h p.o., group II plus lidocaine in a single dose of 4mg/kg s.c., group III was treated with CCl4 for 6 weeks and received x2 at the same dosage as group I, while group VI was treated with CCl4 and the same drug dosage as group II. |
1(0,0,0,1) | Details |