Name | granulocyte colony stimulating factor |
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Synonyms | CSF 3; CSF3; Colony stimulating factor 3; Colony stimulating factor 3 isoform a; Filgrastim; G CSF; GCSF; Granulocyte colony stimulating factor… |
Name | carbon tetrachloride |
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CAS | tetrachloromethane |
PubMed | Abstract | RScore(About this table) | |
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17692581 | Caraceni P, Giannone F, Catani L, Talarico S, Pertosa AM, Domenicali M, Fogli M, Principe A, Trevisani F, Baccarani M, Bernardi M, Lemoli RM: Effects of granulocyte colony stimulating-factor in a rat model of acute liver injury. Dig Liver Dis. 2007 Oct;39(10):943-51. Epub 2007 Aug 9. Recombinant human granulocyte colony stimulating-factor or vehicle was given daily after intoxication (4 days) or before (7 days) and after carbon tetrachloride administration. |
9(0,0,1,4) | Details |
20005281 | Fang B, Luo S, Song Y, Li N, Li H, Zhao RC: Intermittent dosing of G-CSF to ameliorate carbon tetrachloride-induced liver fibrosis in mice. Toxicology. 2010 Mar 30;270(1):43-8. Epub 2009 Dec 11. On the basis of the recent report that granulocyte colony-stimulating factor (G-CSF) administration after rats' partial orthotopic liver transplantation greatly improved survival rate and liver regeneration of partial graft, we here evaluated the effect of intermittent administration of G-CSF on fibrosis formation induced by carbon tetrachloride (CCl (4)). |
6(0,0,1,1) | Details |
18511604 | Kucia MJ, Wysoczynski M, Wu W, Zuba-Surma EK, Ratajczak J, Ratajczak MZ: Evidence that very small embryonic-like stem cells are mobilized into peripheral blood. Stem Cells. 2008 Aug;26(8):2083-92. Epub 2008 May 29. Here, we provide further evidence that under steady-state conditions these cells circulate at very low levels in peripheral blood (PB) ( approximately 100-200 cells/ml) and could be additionally mobilized during pharmacological granulocyte-colony-stimulating factor-induced or stress-related mobilization, as demonstrated in a model of toxic liver or skeletal muscle damage induced by injection of carbon tetrachloride or cardiotoxin, respectively. |
6(0,0,1,1) | Details |
17187438 | Higashiyama R, Inagaki Y, Hong YY, Kushida M, Nakao S, Niioka M, Watanabe T, Okano H, Matsuzaki Y, Shiota G, Okazaki I: Bone marrow-derived cells express matrix metalloproteinases and contribute to regression of liver fibrosis in mice. Hepatology. 2007 Jan;45(1):213-22. To reveal the contribution of bone marrow (BM)-derived cells to the spontaneous regression of liver fibrosis, mice were treated with repeated carbon tetrachloride injections after hematopoietic reconstitution with enhanced green fluorescent protein (EGFP)-expressing BM cells. Therapeutic recruitment of BM cells by granulocyte colony-stimulating factor (G-CSF) treatment significantly enhanced migration of BM-derived cells into fibrotic liver and accelerated the regression of liver fibrosis. |
1(0,0,0,1) | Details |
16374873 | Quintana-Bustamante O, Alvarez-Barrientos A, Kofman AV, Fabregat I, Bueren JA, Theise ND, Segovia JC: Hematopoietic mobilization in mice increases the presence of bone marrow-derived hepatocytes via in vivo cell fusion. Hepatology. 2006 Jan;43(1):108-16. We investigated whether granulocyte colony-stimulating factor (G-CSF)-mediated mobilization of hematopoietic cells increases the phenomenon. Recurrent liver injury in mice expressing green fluorescent protein (EGFP) in all hematopoietic-derived cells was produced by 3 months of carbon tetrachloride (CCL4) injections. |
1(0,0,0,1) | Details |
15661404 | Yannaki E, Athanasiou E, Xagorari A, Constantinou V, Batsis I, Kaloyannidis P, Proya E, Anagnostopoulos A, Fassas A: G-CSF-primed hematopoietic stem cells or G-CSF per se accelerate recovery and improve survival after liver injury, predominantly by promoting endogenous repair programs. Exp Hematol. 2005 Jan;33(1):108-19. OBJECTIVE: On the basis of the recently recognized potential of bone marrow (BM) cells to give rise to hepatocytes, we investigated the possibility that granulocyte colony-stimulating factor (G-CSF)-mobilized BM cells could home to the injured liver and promote tissue repair. |
1(0,0,0,1) | Details |