| Name | hTERT |
|---|---|
| Synonyms | ABG deleted variant of telomerase reverse transcriptase; EST 2; EST2; HEST 2; HEST2; TCS 1; TCS1; TERT… |
| Name | carbon tetrachloride |
|---|---|
| CAS | tetrachloromethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17869215 | Song JS, Murase N, Demetris AJ, Michalopoulos GK, Ochoa ER: Protection from acute cellular injury using Sleeping Beauty mediated telomerase gene transfer. Biochem Biophys Res Commun. 2007 Nov 16;363(2):253-6. Epub 2007 Jun 8. Using the SB transposon system in vitro hTERT gene overexpression has protective effects from acute cellular injury by tert-butyl hydroperoxide (t-BH), carbon tetrachloride (CCl (4)), and d-galactosamine (d-GalN) in normal human cells IMR-90. pT3.hTERT.Con vector and helper plasmid co-transfection resulted in a approximately 3-fold increase in telomerase activity which was maintained for 14 days. |
7(0,0,1,2) | Details |
| 15194652 | Sato R, Maesawa C, Fujisawa K, Wada K, Oikawa K, Takikawa Y, Suzuki K, Oikawa H, Ishikawa K, Masuda T: Prevention of critical telomere shortening by in human normal hepatic cultured cells and carbon tetrachloride induced rat liver fibrosis. Gut. 2004 Jul;53(7):1001-9. To prevent critical telomere shortening in hepatocytes, we have focused on oestrogen dependent transactivation of the human telomerase reverse transcriptase (hTERT) gene as a form of telomerase therapy in chronic liver disease. |
5(0,0,0,5) | Details |
| 16651430 | Farazi PA, Glickman J, Horner J, Depinho RA: Cooperative interactions of p53 mutation, telomere dysfunction, and chronic liver damage in hepatocellular carcinoma progression. Cancer Res. 2006 May 1;66(9):4766-73. Here, in a hepatocellular carcinoma-prone model brought about through toxin-induced hepatocyte injury and regeneration, we sought to determine the cooperative interactions of germ line p53 mutation and telomere dysfunction [produced by telomerase reverse transcriptase (mTERT) gene knockout]. |
1(0,0,0,1) | Details |
| 15112349 | Liu QH, Li DG, Huang X, Zong CH, Xu QF, Lu HM: Suppressive effects of 17beta- on hepatic fibrosis in CCl4-induced rat model. World J Gastroenterol. 2004 May 1;10(9):1315-20. First-passage HSCs were randomly divided into 10 groups, and different concentrations of beta-Est, 2-hydroxyestradiol (2OHE) or (2MeOE) were separately added to the cell groups. |
1(0,0,0,1) | Details |