Protein Information

Name bile salt export pump
Synonyms ABC16; ABCB11; ATP binding cassette sub family B member 11; BSEP; Bile salt export pump; PFIC 2; PFIC2; PGY 4…

Compound Information

Name carbon tetrachloride
CAS tetrachloromethane

Reference List

PubMed Abstract RScore(About this table)
19525466 Bhargava KK, Joseph B, Ananthanarayanan M, Balasubramaniyan N, Tronco GG, Palestro CJ, Gupta S: Adenosine triphosphate-binding cassette subfamily C member 2 is the major transporter of the hepatobiliary imaging agent (99m) Tc-mebrofenin. J Nucl Med. 2009 Jul;50(7):1140-6. Epub 2009 Jun 12.

RESULTS: Carbon tetrachloride and cell transplantation produced hepatic inflammation with activation of Kupffer cells, resulting in a rapid decline in the expression of the bile canalicular transporters Abcb4, Abcb11, and Abcc2.
81(1,1,1,1) Details
18627004 Hannivoort RA, Dunning S, Vander Borght S, Schroyen B, Woudenberg J, Oakley F, Buist-Homan M, van den Heuvel FA, Geuken M, Geerts A, Roskams T, Faber KN, Moshage H: Multidrug resistance-associated proteins are crucial for the viability of activated rat hepatic stellate cells. Hepatology. 2008 Aug;48(2):624-34.


An in vivo model of carbon tetrachloride (CCl (4))-induced liver fibrosis was used.
0(0,0,0,0) Details