Name | p65 |
---|---|
Synonyms | Erythrocyte 65 kDa protein; p65 |
Name | carbon tetrachloride |
---|---|
CAS | tetrachloromethane |
PubMed | Abstract | RScore(About this table) | |
---|---|---|---|
15959796 | Orfila C, Lepert JC, Alric L, Carrera G, Beraud M, Pipy B: Immunohistochemical distribution of activated nuclear factor kappaB and peroxisome proliferator-activated receptors in carbon tetrachloride-induced chronic liver injury in rats. Histochem Cell Biol. 2005 Jun;123(6):585-93. Epub 2005 Jun 15. We investigated the immunohistochemical distribution of active NF-kappaB p65 and peroxisome proliferator-activated receptor (PPAR) subtypes alpha and gamma in the different phases of liver steatonecrosis and cirrhosis induced in rats after 3 and 9 weeks of carbon tetrachloride (CCl4) intoxication. |
7(0,0,1,2) | Details |
16381635 | Liu SQ, Yu JP, He L, Yu HG, Luo HS: [Effects of nuclear factor kappaB and transforming growth factor beta1 in the anti-liver fibrosis process using Ginkgo biloba extract]. Zhonghua Gan Zang Bing Za Zhi. 2005 Dec;13(12):903-7. The expressions of nuclear factor kappaB (NF-kappaB) P65, and alpha-smooth muscle actin (alpha-SMA) were detected by immunohistochemistry. |
2(0,0,0,2) | Details |
18312290 | Yang ZF, Lau CK, Ngai P, Lam SP, Ho DW, Poon RT, Fan ST: Cardiotrophin-1 enhances regeneration of cirrhotic liver remnant after hepatectomy through promotion of angiogenesis and cell proliferation. Liver Int. 2008 May;28(5):622-31. Epub 2008 Feb 26. Administration of CT-1 enhanced the expression of nuclear factor-kappaB (P65), vascular endothelial growth factor (VEGF), CyclinD1 and p42/44 in the liver remnant. |
2(0,0,0,2) | Details |
18397230 | Hisamori S, Tabata C, Kadokawa Y, Okoshi K, Tabata R, Mori A, Nagayama S, Watanabe G, Kubo H, Sakai Y: carbon tetrachloride-induced liver fibrosis in mice through modulating cytokine production. Liver Int. 2008 Nov;28(9):1217-25. Epub 2008 Apr 7. In vitro studies disclosed that the administration of ATRA reduced (i) the production of TGF-beta1, IL-6 and collagen from HSCs, (ii) TGF-beta-dependent transdifferentiation of the cells and IL-6-dependent cell proliferation and (iii) the activities of nuclear factor-kappaB p65 and p38mitogen-activated protein kinase, which stimulate the production of TGF-beta1 and IL-6, which could be the mechanism underlying the preventive effect of ATRA on liver fibrosis. |
ameliorates 1(0,0,0,1) | Details |
17278221 | Dang SS, Wang BF, Cheng YA, Song P, Liu ZG, Li ZF: Inhibitory effects of saikosaponin-d on CCl4-induced hepatic fibrogenesis in rats. World J Gastroenterol. 2007 Jan 28;13(4):557-63. Moreover, the expression of NF-kappaB p65 in the liver of treated groups was lower than that in model groups while the expression of I-kappaBalpha was higher in treated group than in model group (P < 0.01). |
1(0,0,0,1) | Details |
17030452 | Lv P, Luo HS, Zhou XP, Chireyath Paul S, Xiao YJ, Si XM, Liu SQ: Thalidomide prevents rat liver cirrhosis via inhibition of oxidative stress. Pathol Res Pract. 2006;202(11):777-88. Epub 2006 Oct 6. The cirrhosis of rat was induced by intraperitoneal injection of carbon tetrachloride thrice weekly; meanwhile, thalidomide (10mg/kg or 100mg/kg) was given daily by intragastric administration for 8 weeks. Nuclear factor kappa B p65 (NF-kappaBp65) protein in nucleus and transforming growth factor beta1 (TGF-beta1) protein in cytoplasm were detected by Western blot. |
1(0,0,0,1) | Details |