Protein Information

Name NF kappa B
Synonyms DNA binding factor KBF1; EBP 1; KBF 1; KBF1; NF kappa B; NFKB p105; NFKB p50; NFKB 1…

Compound Information

Name carbon tetrachloride
CAS tetrachloromethane

Reference List

PubMed Abstract RScore(About this table)
15730626 Li Y, Li Y, Liu GT: [Protective effects of bicyclol on liver fibrosis induced by carbon tetrachloride]. Zhonghua Yi Xue Za Zhi. 2004 Dec 17;84(24):2096-101.

Twelve and twenty-four hours after the damage by carbon tetrachloride the binding activity of nuclear NF kappa B remained very high in the model group mice and was significantly lower in the 2 bicyclol group mice in comparison with the model mice.
83(1,1,1,3) Details
15760680 Sudo K, Yamada Y, Moriwaki H, Saito K, Seishima M: Lack of tumor necrosis factor receptor type 1 inhibits liver fibrosis induced by carbon tetrachloride in mice. Cytokine. 2005 Mar 7;29(5):236-44.

Furthermore, a marked reduction in procollagen and TGF-beta synthesis was observed in TNFR-1 KO mice, which also had little detectable NF-kappa B, STAT3, and AP1 binding, and reduced levels of liver interleukin-6 (IL-6) mRNA compared to WT and TNFR-2 KO mice.
2(0,0,0,2) Details