Protein Information

Name Alpha fetoprotein regulator
Synonyms AFP regulator 1; RAF; AFR 1; AFR1; Alpha fetoprotein regulator; Alpha fetoprotein regulator 1; Regulator of AFP; Transcription factor ZHX2…

Compound Information

Name carbon tetrachloride
CAS tetrachloromethane

Reference List

PubMed Abstract RScore(About this table)
17668883 Morford LA, Davis C, Jin L, Dobierzewska A, Peterson ML, Spear BT: The oncofetal gene glypican 3 is regulated in the postnatal liver by zinc fingers and homeoboxes 2 and in the regenerating liver by alpha-fetoprotein regulator 2. Hepatology. 2007 Nov;46(5):1541-7.

We also demonstrate that Gpc3 is activated in the regenerating liver following a carbon tetrachloride treatment and that the level of Gpc3 induction is controlled by alpha-fetoprotein regulator 2 (Afr2).
33(0,1,1,3) Details
15767785 Park JK, Feuerman MH: Afr2 regulation occurs cell-autonomously in vitro but is not conferred on episomal DNA in transient assays. DNA Cell Biol. 2005 Mar;24(3):189-98.


The level of AFP gene expression during liver regeneration is regulated by the unlinked, autosomal gene, Alpha-fetoprotein regulator 2 (Afr2).
1(0,0,0,1) Details