Name | S1P |
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Synonyms | MBTPS 1; MBTPS1; MBTPS1 protein; Membrane bound transcription factor site 1 protease precursor; Membrane bound transcription factor site 1 protease; PCSK 8; PCSK8; S1P… |
Name | carbon tetrachloride |
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CAS | tetrachloromethane |
PubMed | Abstract | RScore(About this table) | |
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20188085 | Ikeda H, Ohkawa R, Watanabe N, Nakamura K, Kume Y, Nakagawa H, Yoshida H, Okubo S, Yokota H, Tomiya T, Inoue Y, Nishikawa T, Ohtomo N, Tanoue Y, Koike K, Yatomi Y: Plasma concentration of bioactive lipid mediator reduced in patients with chronic hepatitis C. Clin Chim Acta. 2010 May 2;411(9-10):765-70. Epub 2010 Feb 24. Furthermore, plasma S1P concentration decreased throughout the progression of carbon tetrachloride-induced liver fibrosis in rats. |
is 13(0,0,1,8) | Details |
18955732 | Ikeda H, Watanabe N, Ishii I, Shimosawa T, Kume Y, Tomiya T, Inoue Y, Nishikawa T, Ohtomo N, Tanoue Y, Iitsuka S, Fujita R, Omata M, Chun J, Yatomi Y: fibrosis after liver injury via sphingosine 1-phosphate receptor 2. J Lipid Res. 2009 Mar;50(3):556-64. Epub 2008 Oct 27. Nuclear 5-bromo-2'-deoxy- labeling, proliferating cell nuclear antigen (PCNA) staining in hepatocytes, and the ratio of liver weight to body weight were enhanced at 48 h in S1P (2)-deficient mice after a single carbon tetrachloride (CCl (4)) injection. |
regulates regeneration and 11(0,0,1,6) | Details |
17341687 | Serriere-Lanneau V, Teixeira-Clerc F, Li L, Schippers M, de Wries W, Julien B, Tran-Van-Nhieu J, Manin S, Poelstra K, Chun J, Carpentier S, Levade T, Mallat A, Lotersztajn S: The receptor S1P2 triggers hepatic wound healing. FASEB J. 2007 Jul;21(9):2005-13. Epub 2007 Mar 6. (S1P) is a bioactive sphingolipid produced by kinase (SphK1 and 2). Here we investigated the function of these receptors in the wound healing response to acute liver injury elicited by carbon tetrachloride, a process that associates hepatocyte proliferation and matrix remodeling. |
4(0,0,0,4) | Details |
19398237 | Li C, Kong Y, Wang H, Wang S, Yu H, Liu X, Yang L, Jiang X, Li L, Li L: Homing of bone marrow mesenchymal stem cells mediated by contributes to liver fibrosis. J Hepatol. 2009 Jun;50(6):1174-83. Epub 2009 Mar 29. Moreover, analysis in vivo and in vitro suggested that homing of BMSCs to the damaged liver was in response to (S1P) gradient between liver and BM. Carbon tetrachloride or bile duct ligation was used to induce liver fibrosis. |
3(0,0,0,3) | Details |