| 166156 |
Johnson R, Masserano R, Haring R, Kho B, Schilling G: Quantitative GLC determination of conjugated estrogens in raw materials and finished dosage forms. J Pharm Sci. 1975 Jun;64(6):1007-11.
The method involves slurrying or dissolving a portion of the formulation pH 5.2 buffer, hydrolysis with sulfatase enzyme, extraction with ethylene dichloride, anf finally, GLC separation and quantitation of the corresponding trimethylsilyl ethers on a 2.5% diethylene glycol succinate column. |
6(0,0,1,1) |
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