| Name | GSTA1 1 |
|---|---|
| Synonyms | GST class alpha 1; Gst2; GST class alpha; GST class alpha member 1; GST epsilon; GSTA 1; GSTA1; GSTA1 protein… |
| Name | ethylene dichloride |
|---|---|
| CAS | 1,2-dichloroethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11673082 | Chroust K, Jowett T, Farid-Wajidi MF, Huang JY, Ryskova M, Wolf R, Holoubek I: Activation or detoxification of mutagenic and carcinogenic compounds in transgenic Drosophila expressing human glutathione S-transferase. Mutat Res. 2001 Nov 15;498(1-2):169-79. Sensitivity of transgenic Drosophila melanogaster with expression of a human gene encoding the glutathione S-transferase alpha subunit (GSTA1-1) to 1,2:5,6-dibenzanthracene (DBA) and 1,2-dichloroethane (DCE) was investigated in the somatic mutation and recombination test (SMART). |
5(0,0,0,5) | Details |
| 8330352 | Simula TP, Glancey MJ, Wolf CR: Human glutathione S-transferase-expressing Salmonella typhimurium tester strains to study the activation/detoxification of mutagenic compounds: studies with halogenated compounds, aromatic amines and Carcinogenesis. 1993 Jul;14(7):1371-6. Alpha and pi class GSTs, GSTA1-1 and GSTP1-1, were expressed in Salmonella TA100 using a regulatable tac promoter expression system. The ability of these GST to modulate the mutagenicity of a range of mutagens including ethylene dibromide, ethylene dichloride and methylene dichloride was then investigated. |
2(0,0,0,2) | Details |