Name | Glutathione S transferase pi |
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Synonyms | DFN 7; PI; DFN7; FAEES 3; FAEES3; GST class pi; GST3; GSTP 1… |
Name | ethylene dichloride |
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CAS | 1,2-dichloroethane |
PubMed | Abstract | RScore(About this table) | |
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8330352 | Simula TP, Glancey MJ, Wolf CR: Human glutathione S-transferase-expressing Salmonella typhimurium tester strains to study the activation/detoxification of mutagenic compounds: studies with halogenated compounds, aromatic amines and Carcinogenesis. 1993 Jul;14(7):1371-6. Alpha and pi class GSTs, GSTA1-1 and GSTP1-1, were expressed in Salmonella TA100 using a regulatable tac promoter expression system. The ability of these GST to modulate the mutagenicity of a range of mutagens including ethylene dibromide, ethylene dichloride and methylene dichloride was then investigated. |
2(0,0,0,2) | Details |
10072168 | Pott WA, Benjamin SA, Yang RS: Antagonistic interactions of an arsenic-containing mixture in a multiple organ carcinogenicity bioassay. Cancer Lett. 1998 Nov 27;133(2):185-90. Our results reveal a dose-responsive antagonistic effect of this four-chemical mixture on the development of preneoplastic hepatic lesions (altered hepatocellular foci and glutathione S-transferase pi positive foci) as well as bronchioalveolar hyperplasia and adenoma formation. |
1(0,0,0,1) | Details |