| Name | transferase |
|---|---|
| Synonyms | 4' phosphopantetheinyl transferase; 4' phosphopantetheinyl transferase; AASD PPT; AASDHPPT; AASDPPT; Alpha aminoadipic semialdehyde dehydrogenase phosphopantetheinyl transferase; Aminoadipate semialdehyde dehydrogenase phosphopantetheinyl transferase; CGI 80… |
| Name | ethylene dichloride |
|---|---|
| CAS | 1,2-dichloroethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 7035935 | Tan EL, Hsie AW: Mutagenicity and cytotoxicity of haloethanes as studied in the CHO/HGPRT system. Mutat Res. 1981 Oct;90(2):183-91. When haloethanes were being tested as direct-acting agents in the Chinese hamster ovary cell/- phosphoribosyl transferase (CHO/HGPRT) system, ethylene dibromide (EtBr2) exhibited more cytotoxic and mutagenic activity than ethylene dichloride (EtCl2), and the mixed halogenated congener ethylene bromochloride (EtBrCl) had an intermediate effect. |
6(0,0,1,1) | Details |
| 1636057 | Danni O, Aragno M, Tamagno E, Ugazio G: In vivo studies on halogen compound interactions. Res Commun Chem Pathol Pharmacol. 1992 Jun;76(3):355-66. The compounds were selected on the basis of their metabolic pathways: carbon tetrachloride (CT) and trichlorobromomethane (TCBM) undergo a dehalogenation via P450-dependent enzyme system, 1,2-dichloroethane (DCE) and 1,2-dibromoethane (DBE) are mainly conjugated with the cytosolic (GSH) by means of the GSH-S-transferase. |
2(0,0,0,2) | Details |
| 8378332 | Thier R, Taylor JB, Pemble SE, Humphreys WG, Persmark M, Ketterer B, Guengerich FP: Expression of mammalian glutathione S-transferase 5-5 in Salmonella typhimurium TA1535 leads to base-pair mutations upon exposure to dihalomethanes. Proc Natl Acad Sci U S A. 1993 Sep 15;90(18):8576-80. A plasmid vector containing rat GSH S-transferase 5-5 was transfected into the Salmonella typhimurium tester strain TA1535, which then produced active enzyme. |
2(0,0,0,2) | Details |