| Name | integrins |
|---|---|
| Synonyms | Alpha 11 precursor; HsT18964; ITGA11; Integrin; Integrin alpha 11; Integrin alpha 11 precursor; MSTP018; HsT18964s… |
| Name | ethylene oxide |
|---|---|
| CAS | oxirane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19818492 | Xiong XB, Ma Z, Lai R, Lavasanifar A: The therapeutic response to multifunctional polymeric nano-conjugates in the targeted cellular and subcellular delivery of doxorubicin. Biomaterials. 2010 Feb;31(4):757-68. Epub 2009 Oct 8. Towards this goal, two polymeric DOX nano-conjugates were developed, for which the design was based on the use of multi-functionalized poly (ethylene oxide)-block-poly (epsilon-caprolactone) (PEO-b-PCL) micelles decorated with alphavbeta3 integrin-targeting ligand (i.e. |
81(1,1,1,1) | Details |
| 17315946 | Xiong XB, Mahmud A, Uludag H, Lavasanifar A: Conjugation of --aspartic acid peptides to poly (ethylene oxide)-b-poly (epsilon-caprolactone) micelles for enhanced intracellular drug delivery to metastatic tumor cells. Biomacromolecules. 2007 Mar;8(3):874-84. Epub 2007 Feb 22. An --aspartic acid (RGD) containing model peptide was conjugated to the surface of poly (ethylene oxide)-block-poly (epsilon-caprolactone) (PEO-b-PCL) micelles as a ligand that can recognize adhesion molecules overexpressed on the surface of metastatic cancer cells, that is, integrins, and that can enhance the micellar delivery of encapsulated hydrophobic drug into a tumor cell. |
81(1,1,1,1) | Details |
| 17896765 | Hu Z, Luo F, Pan Y, Hou C, Ren L, Chen J, Wang J, Zhang Y: Arg-Gly-Asp (RGD) peptide conjugated poly (lactic acid)-poly (ethylene oxide) micelle for targeted drug delivery. J Biomed Mater Res A. 2008 Jun 1;85(3):797-807. The cell-binding assay showed that PLA-PEO-RGD micelle (IC (50) = 11.13 +/- 1.38 nmol/L) had about 3.6-fold higher integrin avidity than PLA-PEO-RGD conjugates (IC (50) = 40.33 +/- 3.12 nmol/L). |
2(0,0,0,2) | Details |
| 19545894 | George PA, Doran MR, Croll TI, Munro TP, Cooper-White JJ: Nanoscale presentation of cell adhesive molecules via block copolymer self-assembly. Biomaterials. 2009 Sep;30(27):4732-7. Epub 2009 Jul 9. Recently, the control of integrin spacing and cellular shape has been shown to affect fundamental biological processes, such as differentiation and apoptosis. Here, we present the self-assembly of maleimide functionalised polystyrene-block-poly (ethylene oxide) copolymers as a simple, yet highly precise method for controlling the position of cellular adhesion molecules. |
1(0,0,0,1) | Details |
| 17877394 | Kuhlman W, Taniguchi I, Griffith LG, Mayes AM: Interplay between PEO tether length and ligand spacing governs cell spreading on RGD-modified PMMA-g-PEO comb copolymers. Biomacromolecules. 2007 Oct;8(10):3206-13. Epub 2007 Sep 18. The effects of tether length on cell adhesion to poly (methyl methacrylate)-graft-poly (ethylene oxide), PMMA-g-PEO, comb copolymer films functionalized with the adhesion peptide RGD were investigated. Fluorescence resonance energy transfer (FRET) measurements indicated a mean separation between integrin-bound peptides of 15.6 +/- 1.4 nm for combs with long (22-mer) tethers, compared with 17.5 +/- 1.3 nm for short (10-mer) tethers, on films of comparable peptide density (approximately 2500 peptides/microm2). |
1(0,0,0,1) | Details |
| 18837524 | He X, Ma J, Jabbari E: Effect of grafting RGD and BMP-2 protein-derived peptides to a hydrogel substrate on osteogenic differentiation of marrow stromal cells. Langmuir. 2008 Nov 4;24(21):12508-16. Epub 2008 Oct 7. The RGD peptides of ECM proteins interact with BMS cells through integrin surface receptors to facilitate cell spreading and adhesion. Poly (lactide-co-ethylene oxide- co- (PLEOF) macromer was cross-linked with Ac-GRGD peptide and propargyl acrylate to produce an RGD conjugated hydrogel. |
1(0,0,0,1) | Details |