| Name | NAT2 |
|---|---|
| Synonyms | ATA 1; NAT2; SAT1; ATA1; Amino acid transporter system A1; N system amino acid transporter 2; SLC38A1; SLC38A1 protein… |
| Name | ethylene oxide |
|---|---|
| CAS | oxirane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15055296 | Norppa H: Cytogenetic biomarkers. IARC Sci Publ. 2004;(157):179-205. These findings may be explained by reduced detoxification capacity rendered by the altered gene and may be linked with exposure to, for example, heterocyclic amines in the case of NAT2 and endogenously formed ethylene oxide in the case of GSTT1. |
32(0,1,1,2) | Details |
| 12872524 | Thier R, Bruning T, Roos PH, Rihs HP, Golka K, Ko Y, Bolt HM: Markers of genetic susceptibility in human environmental hygiene and toxicology: the role of selected CYP, NAT and GST genes. Int J Hyg Environ Health. 2003 Jun;206(3):149-71. The acetylator status for NAT2 can be determined by genotyping or by phenotyping. The human polymorphic GST catalysing conjugation of halomethanes, dihalomethanes, ethylene oxide and a number of other industrial compounds could be characterised as a class theta enzyme (GSTT1) by means of molecular biology. "Conjugator" and "non-conjugator" phenotypes are coincident with the presence and absence of the GSTT1 gene. |
2(0,0,0,2) | Details |