| Name | caspase 3 |
|---|---|
| Synonyms | Apopain; CASP 3; CASP3; CPP 32; CPP32; CPP32B; Caspase 3; Caspase 3 precursor… |
| Name | methylene chloride |
|---|---|
| CAS | dichloromethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15369734 | Cha YY, Lee EO, Lee HJ, Park YD, Ko SG, Kim DH, Kim HM, Kang IC, Kim SH: Methylene chloride fraction of Scutellaria barbata induces apoptosis in human U937 leukemia cells via the mitochondrial signaling pathway. Clin Chim Acta. 2004 Oct;348(1-2):41-8. METHODS: With methylene chloride fraction of Herba Scutellariae barbatae (MCSB), apoptosis-related experiments were carried out on human U937 leukemia cells by (a) 2,3-bis [2-4-nitro-5-sulphophenyl] 2H-tetrazolium-5-carboxanilide (XTT) assay for cytotoxicity; (b) terminal deoxynucleotidyl-transferase-mediated nick end labeling (TUNEL) assay for morphological changes; (c) cell cycle analysis; (d) Western blot analysis of poly (ADP- polymerase (PARP), caspase-8, caspase-9, caspase-3 and Bax, Bcl-2 and cytochrome c expressions for apoptosis signaling pathway. |
32(0,1,1,2) | Details |
| 15340217 | Ha ES, Lee EO, Yoon TJ, Kim JH, Park JO, Lim NC, Jung SK, Yoon BS, Kim SH: Methylene chloride fraction of Spatholobi Caulis induces apoptosis via caspase dependent pathway in U937 cells. Biol Pharm Bull. 2004 Sep;27(9):1348-52. Western blotting revealed that MCSC activated caspase-3 expression and cleaved poly (ADP- polymerase (PARP) in a concentration-dependent manner. |
2(0,0,0,2) | Details |
| 14512878 | Sass G, Soares MC, Yamashita K, Seyfried S, Zimmermann WH, Eschenhagen T, Kaczmarek E, Ritter T, Volk HD, Tiegs G: Heme oxygenase-1 and its reaction product, prevent inflammation-related apoptotic liver damage in mice. Hepatology. 2003 Oct;38(4):909-18. Exogenous CO administration or treatment with the CO-releasing agent methylene chloride mimicked the protective effect of HO-1, whereas treatment with exogenous or overexpression of ferritin by recombinant adenoviral gene transfer did not. |
0(0,0,0,0) | Details |