Protein Information

Name Ah receptor
Synonyms AHR; Ah receptor; AhR; Aryl hydrocarbon receptor; Aryl hydrocarbon receptor precursor; Dioxin receptor; Ah receptors; AhRs…

Compound Information

Name methylene chloride
CAS dichloromethane

Reference List

PubMed Abstract RScore(About this table)
9841810 Meek MD: Ah receptor and estrogen receptor-dependent modulation of gene expression by extracts of diesel exhaust particles. Environ Res. 1998 Nov;79(2):114-21.

The ability of a methylene chloride extract of diesel exhaust particle (EDEP) to activate the aryl hydrocarbon receptor (AhR), bind to and activate the estrogen receptor (ER), and induce gene expression mediated via these nuclear receptors was examined in Hepa1c1c7 mouse hepatoma and MCF-7 human breast cancer cells.
83(1,1,1,3) Details
8785012 Hansen LG, O'Keefe PW: Polychlorinated dibenzofurans and dibenzo-p-dioxins in subsurface soil, superficial dust, and air extracts from a contaminated landfill. Arch Environ Contam Toxicol. 1996 Aug;31(2):271-6.


The different extracts show subtle differences in toxicities and the soil extract has been shown to cause both Ah receptor mediated effects and Ah receptor independent effects in immature female rats.
1(0,0,0,1) Details
11223170 Heo Y, Saxon A, Hankinson O: Effect of diesel exhaust particles and their components on the allergen-specific IgE and IgG1 response in mice. Toxicology. 2001 Feb 28;159(3):143-58.


DEP were extracted with methylene chloride.
0(0,0,0,0) Details