| Name | cytochrome c |
|---|---|
| Synonyms | CYC; CYCS; Cytochrome C; HCS; Cytochrome Cs |
| Name | naphthalene |
|---|---|
| CAS | naphthalene |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19277727 | Alam Khan MK, Das U, Rahaman MH, Hassan MI, Srinivasan A, Singh TP, Ahmad F: A single mutation induces molten globule formation and a drastic destabilization of wild-type cytochrome c at pH 6.0. J Biol Inorg Chem. 2009 Jun;14(5):751-60. Epub 2009 Mar 10. Characterization of this mutant by the far-UV, near-UV, and Soret circular dichroism, intrinsic and 1-Anilino-8-naphthalene sulfonate fluorescence, and dynamic light scattering measurements led to the conclusion that the L94G mutant has all the common structural characteristics of a molten globule at pH 6.0 and 25 degrees C. |
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| 17125458 | Naeem A, Ashraf MT, Akram M, Khan RH: Comparative study of effects of polyols, salts, and on trichloroacetic acid-induced state of cytochrome C. Biochemistry. 2006 Oct;71(10):1101-9. Addition of 70% (v/v) polyols to TCA (3.3 mM)-induced state of Cyt c resulted in increased 1-anilino-8-naphthalene sulfonate binding and increased mean residue ellipticity at 222 nm, indicating increase in compactness with enhanced exposure of hydrophobic surface area. |
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| 17419653 | Domenech O, Redondo L, Montero MT, Hernandez-Borrell J: Specific adsorption of cytochrome C on -glycerophospholipid monolayers and bilayers. Langmuir. 2007 May 8;23(10):5651-6. Epub 2007 Apr 10. The competition between 8-anilino-1-naphthalene sulfonate (ANS) and cyt c for the same binding sites in liposomes that have identical nominal compositions with respect to those of the monolayers was used to obtain binding parameters. |
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| 20065042 | Zhang Y, Soto J, Park K, Viswanath G, Kuwada S, Abel ED, Wang L: Nuclear receptor SHP, a death receptor that targets mitochondria, induces apoptosis and inhibits tumor growth. Mol Cell Biol. 2010 Mar;30(6):1341-56. Epub 2010 Jan 11. SHP is a pivotal cell death receptor that targets mitochondria, where it binds with Bcl-2, disrupts Bcl-2/Bid interaction, and induces cytochrome c release. The apoptosis inducer AHPN {retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid} acts by regulating SHP gene expression and promotes the translocation of SHP from the nucleus to the mitochondria. |
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| 17907278 | Domenech O, Redondo L, Picas L, Morros A, Montero MT, Hernandez-Borrell J: Atomic force microscopy characterization of supported planar bilayers that mimic the mitochondrial inner membrane. J Mol Recognit. 2007 Nov-Dec;20(6):546-53. We observed: (i) that the thickness of the bilayers, calculated from a cross-sectional analysis, decreased as the visualization temperature increased; (ii) the existence of laterally segregated domains that respond to temperature in SPBs of POPE:POPC:CL; (iii) a decrease in height and an increase in roughness (Ra) of SPBs after cytochrome c (cyt c) injection at room temperature. To obtain further insight into the nature of the interaction between cyt c and the bilayers, the competition between 8-anilino-1-naphthalene sulfonate (ANS) and the protein for the same binding sites in liposomes was monitored by fluorescence. |
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| 17150035 | Zhang XK: Targeting Nur77 translocation. Expert Opin Ther Targets. 2007 Jan;11(1):69-79. In contrast, it is a potent killer when migrating to mitochondria, where it binds to Bcl-2 and converts its survival phenotype, triggering cytochrome c release and apoptosis. Agents, such as 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (AHPN/CD437), which induce Nur77 migration from the nucleus to mitochondria, effectively induce apoptosis of cancer cells. |
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| 18922933 | Subramaniam D, Giridharan P, Murmu N, Shankaranarayanan NP, May R, Houchen CW, Ramanujam RP, Balakrishnan A, Vishwakarma RA, Anant S: Activation of apoptosis by 1--5,7-dimethoxy-2-naphthalene-carboxaldehyde, a novel compound from Aegle marmelos. Cancer Res. 2008 Oct 15;68(20):8573-81. Moreover, caspase-8 and Bid activation, and cytochrome c release, were observed, suggesting the existence of a cross-talk between death receptor and the mitochondrial pathways. |
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| 18534571 | Mikami M, Goubaeva F, Song JH, Lee HT, Yang J: beta-Adrenoceptor blockers protect against staurosporine-induced apoptosis in SH-SY5Y neuroblastoma cells. Eur J Pharmacol. 2008 Jul 28;589(1-3):14-21. Epub 2008 Apr 25. We studied the effects of three beta-adrenoceptor blockers (1-(isoproplyamino)-3-(naphthalene-1-yloxy) propan-2-ol), (2-[4-[2-hydroxy-3-(1-methylethylamino) propoxyl] phenyl] ehanamide), and ICI 118551 (1-[2,3-(dihydro-7-methyl-1H-iden-4-yl) oxy]-3-[(1-methylethyl) amino]-2-but anol), against staurosporine-induced apoptosis in SH-SY5Y human neuroblastoma cells. In isolated mitochondria, and ICI 118551 inhibited staurosporine-induced cytochrome c release while did not. |
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| 20348302 | Yagi JM, Suflita JM, Gieg LM, Derito CM, Jeon CO, Madsen EL: Subsurface cycling of and anaerobic aromatic hydrocarbon biodegradation shown by nucleic acid and metabolic biomarkers. Appl Environ Microbiol. 2010 Mar 26. GC/MS detection of two carboxylated naphthalene metabolites and transcribed benzylsuccinate synthase, cytochrome c reductase, and monooxygenase genes indicated that anaerobic metabolism of aromatic compounds and that both dissimilatory reduction to (DNRA) and nitrification were in progress in situ. |
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| 16584204 | Moza B, Qureshi SH, Islam A, Singh R, Anjum F, Moosavi-Movahedi AA, Ahmad F: A unique molten globule state occurs during unfolding of cytochrome c by LiClO4 near physiological pH and temperature: structural and thermodynamic characterization. Biochemistry. 2006 Apr 11;45(14):4695-702. The stable folding intermediate state has been characterized by near- and far-UV circular dichroism, fluorescence, 8-anilino-1-naphthalene (ANS) binding, and intrinsic viscosity measurements. |
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