| 18400335 |
Du H, Wang J, Zhang X, Hu Z: A novel quantitative structure-activity relationship method to predict the affinities of MT3 melatonin binding site. Eur J Med Chem. 2008 Dec;43(12):2861-9. Epub 2008 Feb 29.
The linear regression (LR) and non-linear regression methods--grid search-support vector machine (GS-SVM) and projection pursuit regression (PPR) were used to develop quantitative structure-activity relationship (QSAR) models for a series of derivatives of naphthalene, benzofurane and indole with respect to their affinities to MT3/quinone reductase 2 (QR2) melatonin binding site. |
34(0,1,1,4) |
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