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Bera A, Nandi PK: Biological polyamines inhibit nucleic-acid-induced polymerisation of prion protein. Arch Virol. 2007;152(4):655-68. Epub 2007 Jan 15.
Nucleic-acid-induced polymerisation of prion protein, when monitored by anilino naphthalene sulfonic acid dye, shows, successively, an immediate fluorescence increase of the dye upon mixing of the reactants, followed by a lag period in which the dye fluorescence remains unchanged, and then a phase in which dye fluorescence increases with time. |
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