| 19713358 |
Bui PH, Hankinson O: Functional characterization of human cytochrome P450 2S1 using a synthetic gene-expressed protein in Escherichia coli. Mol Pharmacol. 2009 Nov;76(5):1031-43. Epub 2009 Aug 27.
However, the oxidative activity of CYP2S1 was supported by cumene hydroperoxide or H (2) O (2), such that CYP2S1 oxidized many important environmental carcinogens, including benzo [a] pyrene, 9,10-dihydro-benzo [a] pyrene, 7,12-dimethylbenz [a] anthracene, benzo [a] pyrene-7,8-dihydrodiol, aflatoxin B1, naphthalene, and styrene, with high turnover. |
36(0,1,1,6) |
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