Protein Information

Name MT1
Synonyms MEL 1A R; MT1; MTNR1A; Mel1a melatonin receptor; Melatonin receptor 1A; Melatonin receptor type 1A; Mel1a melatonin receptors; Melatonin receptor 1As…

Compound Information

Name naphthalene
CAS naphthalene

Reference List

PubMed Abstract RScore(About this table)
18583104 San L, Arranz B: Agomelatine: a novel mechanism of antidepressant action involving the melatonergic and the serotonergic system. Eur Psychiatry. 2008 Sep;23(6):396-402. Epub 2008 Jun 25.

Agomelatine, a naphthalene analog of melatonin, is both an agonist of human cloned melatonergic MT1 and MT2 receptors and a serotonin 5-HT2C receptor antagonist.
81(1,1,1,1) Details
17557804 Atkinson JJ, Toennies HM, Holmbeck K, Senior RM: Membrane type 1 matrix metalloproteinase is necessary for distal airway epithelial repair and keratinocyte growth factor receptor expression after acute injury. Am J Physiol Lung Cell Mol Physiol. 2007 Sep;293(3):L600-10. Epub 2007 Jun 8.

Since other MMPs are involved in bronchial epithelial repair, we investigated the role of MT1-MMP in naphthalene-induced small airway injury and repair in wild-type (WT) and MT1-MMP-knockout (KO) mice.
12(0,0,1,7) Details