Protein Information

Name MD 2
Synonyms ESOP 1; ESOP1; LY96; Lymphocyte antigen 96 precursor; MD 2; MD 2 protein; MD2; MD2 protein…

Compound Information

Name naphthalene
CAS naphthalene

Reference List

PubMed Abstract RScore(About this table)
19473973 Mancek-Keber M, Gradisar H, Inigo Pestana M, Martinez de Tejada G, Jerala R: Free thiol group of MD-2 as the target for inhibition of the lipopolysaccharide-induced cell activation. J Biol Chem. 2009 Jul 17;284(29):19493-500. Epub 2009 May 27.

Fluorescent compounds 2-(4'-(iodoacetamido) anilino) naphthalene-6-sulfonic acid and N-pyrene maleimide formed a covalent bond with MD-2 through Cys (133) and inhibited LPS signaling.
37(0,1,1,7) Details