| 8806906 |
Bouzeghrane F, Fagette S, Somody L, Allevard AM, Gharib C, Gauquelin G: Restraint vs. hindlimb suspension on fluid and electrolyte balance in rats. J Appl Physiol. 1996 Jun;80(6):1993-2001.
To determine the effect of hindlimb suspension on body fluid volume, salt and water balance, and relevant hormones, two series of experiments were performed in an experimental protocol including periods of isolation (7 days), horizontal attachment (7 days), and suspension (14 days). 1) During the first experiment, water and electrolyte balance, arginine vasopressin (AVP), and guanosine 3',5'- cyclic monophosphate (cGMP) were determined in urine, atrial natriuretic peptide in plasma and atria, and renin concentration and AVP in plasma in 30 rats. 2) During the second experiment, blood volume and extracellular fluid volume were measured by a dilution technique (Evans blue and sodium thiocyanate) in another 30 rats. |
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