Protein Information

Name NF E2 related factor 2
Synonyms HEBP 1; HEBP1; NF E2 related factor 2; NFE2 related factor 2; NFE2 related trancription factor 2; NFE2L2; NRF 2; NRF2…

Compound Information

Name nicotine
CAS

Reference List

PubMed Abstract RScore(About this table)
19656028 Lee HJ, Pi SH, Kim Y, Kim HS, Kim SJ, Kim YS, Lee SK, Kim EC: Effects of nicotine on antioxidant defense enzymes and RANKL expression in human periodontal ligament cells. J Periodontol. 2009 Aug;80(8):1281-8.

Nicotine induced the synthesis of the transcription factor NF-E2-related factor-2 (Nrf2) as well as a number of cellular antioxidants and phase II enzymes, such as heme oxygenase-1.
81(1,1,1,1) Details