Name | DRD3 |
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Synonyms | D(3) dopamine receptor; D3DR; DRD 3; DRD3; Dopamine receptor D3; Dopamine receptor D3 isoform a; ETM 1; ETM1… |
Name | nicotine |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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19995481 | Khaled MA, Farid Araki K, Li B, Coen KM, Marinelli PW, Varga J, Gaal J, Le Foll B: The selective receptor antagonist SB 277011-A, but not the partial agonist BP 897, blocks cue-induced reinstatement of nicotine-seeking. Int J Neuropsychopharmacol. 2010 Mar;13(2):181-90. Epub 2009 Dec 9. SB 277011-A (1-10 mg/kg) was able to block cue-induced reinstatement of nicotine-seeking, indicating that DRD3 selective antagonism may be an effective approach to prevent relapse for nicotine. |
D3 33(0,1,1,3) | Details |
19179847 | Le Foll B, Gallo A, Le Strat Y, Lu L, Gorwood P: Genetics of receptors and drug addiction: a comprehensive review. Behav Pharmacol. 2009 Feb;20(1):1-17. Addictive substances, such as opioids, psychostimulants and nicotine, induce pleasant states or relieve distress, effects that contribute to their recreational use. Here, we will review the information collected implicating the receptors of the D1 family (DRD1 and DRD5) and of the D2 family (DRD2, DRD3 and DRD4) in drug addiction. |
1(0,0,0,1) | Details |