Name | tyrosine hydroxylase |
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Synonyms | Putative tyrosine hydroxylase variant; TH; TH protein; TYH; Truncated tyrosine hydroxylase; Tyrosine 3 hydroxylase; Tyrosine 3 monooxygenase; Tyrosine hydroxylase… |
Name | nicotine |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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19406037 | Naha N, Lee HY, Hwang JS, Bahk JY, Park MS, Lee SY, Kim SH, Kim MO: Nicotine tolerance to PC12 cell line: acute and chronic exposures modulate dopamine D2 receptor and tyrosine hydroxylase expression. Neurol Res. 2009 Apr;31(3):289-99. |
243(3,3,3,3) | Details |
19476543 | Radcliffe PM, Sterling CR, Tank AW: Induction of tyrosine hydroxylase mRNA by nicotine in rat midbrain is inhibited by mifepristone. J Neurochem. 2009 Jun;109(5):1272-84. Epub 2009 Mar 23. |
38(0,1,2,3) | Details |
19594327 | Singh S, Singh K, Patel DK, Singh C, Nath C, Singh VK, Singh RK, Singh MP: The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype and nicotine-mediated neuroprotection. Rejuvenation Res. 2009 Jun;12(3):185-97. Tyrosine hydroxylase (TH)-immunoreactivity in the substantia nigra, the expression of nicotinic acetylcholine receptors (nAChRs) alpha6 and alpha4, content, and 1-methyl-4-phenylpyridinium ion (MPP (+)) level in the striatum were measured to confirm the MPTP-induced PD phenotype and nicotine-mediated neuroprotection. |
31(0,1,1,1) | Details |
19786030 | Schemann M, Hafsi N, Michel K, Kober OI, Wollmann J, Li Q, Zeller F, Langer R, Lee K, Cellek S: The beta3-adrenoceptor agonist GW427353 (Solabegron) decreases excitability of human enteric neurons via release of somatostatin. Gastroenterology. 2010 Jan;138(1):266-74. Epub 2009 Sep 25. Tissue perfusion with GW427353 reduced nicotine-evoked neuronal spike frequency, an effect prevented by the beta3-AR antagonist SR-59230 and the SST2-receptor antagonist CYN154806 and mimicked by the SST2 receptor agonist octreotide. Immunohistochemistry was used to detect adiponectin, beta3-AR, SST, SST2 receptors, tyrosine hydroxylase (TH), and protein gene product 9.5. |
1(0,0,0,1) | Details |
20190011 | Oliveira E, Pinheiro C, Santos-Silva A, Trevenzoli I, Abreu-Villaca Y, Nogueira Neto J, Reis A, Passos M, Moura E, Lisboa P: Nicotine exposure affects mother's and pup's nutritional, biochemical and hormonal profiles during lactation in rats. J Endocrinol. 2010 Feb 26. The 15 days-old NIC-pups presented higher total body fat, higher HDL- serum leptin, serum and catecholamine content, but lower tyrosine hydroxylase protein levels. |
1(0,0,0,1) | Details |
19685015 | Quik M, Campos C, Parameswaran N, Langston JW, McIntosh JM, Yeluashvili M: Chronic nicotine treatment increases nAChRs and microglial expression in monkey substantia nigra after nigrostriatal damage. J Mol Neurosci. 2010 Jan;40(1-2):105-13. Epub 2009 Aug 15. |
0(0,0,0,0) | Details |