Protein Information

Name cholinesterase
Synonyms Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase…

Compound Information

Name crufomate
CAS 2-chloro-4-(1,1-dimethylethyl)phenyl methyl methylphosphoramidate

Reference List

PubMed Abstract RScore(About this table)
6454716 Khan MA: Reproduction and growth of progeny of female mice mated after treatment with crufomate. J Environ Sci Health B. 1981;16(2):141-57.

Each treatment with crufomate caused about 50% reversible inhibition of cholinesterase activity without inducing any signs of toxicity.
81(1,1,1,1) Details
7904465 Mason HJ, Waine E, Stevenson A, Wilson HK: Aging and spontaneous reactivation of human plasma cholinesterase activity after inhibition by organophosphorus pesticides. Hum Exp Toxicol. 1993 Nov;12(6):497-503.

No spontaneous reactivation was detected in human plasma ChE inhibited by the methoxy-ethylamino substituted OP (propetamphos) or the methoxy-methylamino substituted OP (crufomate) during 45 hours incubation at 37 degrees C.
2(0,0,0,2) Details