| Name | cholinesterase |
|---|---|
| Synonyms | Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase… |
| Name | acephate |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 3989221 | Hussain MA, Mohamad RB, Oloffs PC: Studies on the toxicity, metabolism, and anticholinesterase properties of acephate and methamidophos. J Environ Sci Health B. 1985 Feb;20(1):129-47. The toxicity of acephate to four species of aquatic insects, as well as the metabolism and cholinesterase-inhibiting properties of the chemical in the rat were studied. |
276(3,4,4,6) | Details |
| 7154130 | Ando M, Wakamatsu K: Inhibitory effect of acephate (N-acetyl O, S-dimethyl thiophosphoramide) on serum cholinesterase--effect of acephate on cholinesterase. J Toxicol Sci. 1982 Aug;7(3):185-92. Acephate, one of the organophosphorous insecticides, inhibited the activity of cholinesterase. |
228(2,4,4,8) | Details |
| 2241237 | Maroni M, Catenacci G, Galli D, Cavallo D, Ravazzani G: Biological monitoring of human exposure to acephate. . Arch Environ Contam Toxicol. 1990 Sep-Oct;19(5):782-8. Acephate is a water-soluble organophosphate insecticide whose action on insects has been related to its conversion to methamidophos, a very potent anticholinesterase agent which has caused delayed neuropathy in man. |
87(1,1,2,2) | Details |
| 1178696 | Klaverkamp JF, Hobden BR, Harrison SE: Acute lethality and in vitro brain cholinesterase inhibition of acephate and fenitrothion in rainbow trout. Proc West Pharmacol Soc. 1975;18:358-61. |
81(1,1,1,1) | Details |
| 4060156 | Singh AK: Kinetic analysis of inhibition of brain and red blood cell acetylcholinesterase and plasma cholinesterase by acephate or methamidophos. Toxicol Appl Pharmacol. 1985 Nov;81(2):302-9. |
62(0,2,2,2) | Details |
| 6491173 | Chukwudebe AC, Hussain MA, Oloffs PC: Hydrolytic and metabolic products of acephate in water and mouse liver. . J Environ Sci Health B. 1984 Aug;19(6):501-22. Acephate toxicity to aquatic insects would depend on its persistence in water, its uptake by the insects, its conversion to methamidophos, and the combined inhibitory effect of acephate and methamidophos on the cholinesterase enzyme. |
43(0,1,3,3) | Details |
| 7459456 | Zinkl JG, Roberts RB, Henny CJ, Lenhart DJ: Inhibition of brain cholinesterase activity in forest birds and squirrels exposed to aerially applied acephate. Bull Environ Contam Toxicol. 1980 May;24(5):676-83. |
31(0,1,1,1) | Details |
| 3798464 | Singh AK: Kinetic analysis of acetylcholinesterase inhibition by combinations of acephate and methamidophos. Toxicology. 1986 Dec 15;42(2-3):143-56. Acephate pre-exposure provided protection against the inhibition of RBC and brain acetylcholinesterase (AChE), and plasma cholinesterase (ChE) activities in rats exposed to both acephate and methamidophos. |
31(0,1,1,1) | Details |
| 2729280 | Ames RG, Brown SK, Mengle DC, Kahn E, Stratton JW, Jackson RJ: Cholinesterase activity depression among California agricultural pesticide applicators. Am J Ind Med. 1989;15(2):143-50. Pesticides most frequently associated with cholinesterase depressions exceeding California threshold values included mevinphos (Phosdrin), oxydemeton methyl (Metasystox-R), methomyl (Lannate), and acephate (Orthene); these pesticides included organophosphates in toxicity categories I and II and one in toxicity category I. |
9(0,0,1,4) | Details |
| 7338949 | Fleming WJ, Bradbury SP: Recovery of cholinesterase activity in mallard ducklings administered organophosphorus pesticides. J Toxicol Environ Health. 1981 Nov-Dec;8(5-6):885-97. Oral doses of the organophosphorus pesticides acephate, dicrotophos, fensulfothion, fonofos, malathion, and parathion were administered to mallard ducklings (Anas platyrhynchos), and brain and plasma cholinesterase (ChE) activities were determined for up to 17 d after dosing. |
7(0,0,1,2) | Details |
| 7224670 | Zinkl JG, Roberts RB, Shea PJ, Lasmanis J: Toxicity of acephate and methamidophos to dark-eyed juncos. Arch Environ Contam Toxicol. 1981;10(2):185-92. Brain cholinesterase (ChE) activity in birds that died after acephate poisoning was depressed 80% below that of control birds. |
6(0,0,1,1) | Details |
| 3814849 | Zinkl JG, Shea PJ, Nakamoto RJ, Callman J: Effects on cholinesterases of rainbow trout exposed to acephate and methamidophos. Bull Environ Contam Toxicol. 1987 Jan;38(1):22-8. |
6(0,0,1,1) | Details |
| 3814841 | Hussain MA: Anticholinesterase properties of methamidophos and acephate in insects and mammals. Bull Environ Contam Toxicol. 1987 Jan;38(1):131-8. |
6(0,0,1,1) | Details |
| 15389333 | Maul JD, Farris JL: Monitoring exposure of passerines to acephate, dicrotophos, and malathion using cholinesterase reactivation. Bull Environ Contam Toxicol. 2004 Oct;73(4):682-9. |
6(0,0,1,1) | Details |
| 15800032 | Moser VC, Casey M, Hamm A, Carter WH Jr, Simmons JE, Gennings C: Neurotoxicological and statistical analyses of a mixture of five organophosphorus pesticides using a ray design. Toxicol Sci. 2005 Jul;86(1):101-15. Epub 2005 Mar 30. In this study, we tested for interaction (s) in a mixture of five organophosphorus (OP) pesticides (chlorpyrifos, diazinon, dimethoate, acephate, and malathion). A series of behavioral measures were evaluated in adult male Long-Evans rats at the time of peak effect following a single oral dose, and then tissues were collected for measurement of cholinesterase (ChE) activity. |
2(0,0,0,2) | Details |
| 6968357 | Hall RJ, Kolbe E: Bioconcentration of organophosphorus pesticides to hazardous levels by amphibians. J Toxicol Environ Health. 1980 Jul;6(4):853-60. Frogs are resistant to cholinesterase inhibitors; thus it was suspected that they might accumulate the pesticides. Dicrotophos, malathion, and acephate were not accumulated to levels such that they were lethal when consumed in a single meal by ducks. |
2(0,0,0,2) | Details |
| 15180375 | Printes LB, Callaghan A: A comparative study on the relationship between acetylcholinesterase activity and acute toxicity in Daphnia magna exposed to anticholinesterase insecticides. Environ Toxicol Chem. 2004 May;23(5):1241-7. Acetylcholinesterase (AChE) activity was measured in Daphnia magna that had been exposed to four organophosphates (OPs; parathion, chlorpyrifos, malathion, and acephate) and one (propoxur) for 48 h. |
1(0,0,0,1) | Details |
| 19415590 | Chang A, Montesano MA, Barr D, Thomas J, Geller R: Urinary elimination kinetics of acephate and its metabolite, methamidophos, in urine after acute ingestion. J Med Toxicol. 2009 Jun;5(2):68-72. Ingestion of AP was confirmed by the presence of urinary AP and MP and severely depressed red blood cell (RBC) cholinesterase and pseudocholinesterase activity levels. |
1(0,0,0,1) | Details |
| 2593091 | Audegond L, Catez D, Foulhoux P, Fournex R, Le Rumeur C, L'Hotellier M, Stepniewski JP: [Potentiation of deltamethrin toxicity by organophosphorus insecticides] . J Toxicol Clin Exp. 1989 May-Jun;9(3):163-76. Others (methyl-parathion, acephate, phosphamidon, monocrotophos) have no such effects, even if they have a very high intrinsic toxicity. Cholinesterase inhibitors of the group are ineffective. |
1(0,0,0,1) | Details |
| 20021020 | Das GP, Jamil K, Rahman MF: Effect of four organophosphorus compounds on human blood acetylcholinesterase: in vitro studies. Toxicol Mech Methods. 2006;16(8):455-9. The aim of the study was to determine the IC50 concentration of the pesticides monocrotophos, chlorpyrifos, profenofos, and acephate as inhibitors of AChE. Cholinesterase was spectrophotometrically measured using acetylthiocholine iodide (AChI) as substrate and dithiobisnitrobenzoic acid (DTNB) as the coloring agent using different aliquots of the pesticides. |
1(0,0,0,1) | Details |
| 16078501 | Tanaka T, Tanaka N, Kita T, Kasai K, Sato H: Acephate in biological fluids of two autopsy cases after ingestion of the chemical. J Forensic Sci. 2005 Jul;50(4):933-6. Serum pseudocholinesterase (ChE) activity was inhibited. |
1(0,0,0,1) | Details |
| 12597033 | Thapar A, Sandhir R, Kiran R: Acephate induced oxidative damage in erythrocytes. . Indian J Exp Biol. 2002 Aug;40(8):963-6. Activities of acetyl cholinesterase and glucose-6-phosphate dehydrogenase decreased, while those of glutathione-s-transferase and glutathione reductase increased. |
1(0,0,0,1) | Details |
| 10197479 | Panemangalore M, Dowla HA, Byers ME: Occupational exposure to agricultural chemicals: effect on the activities of some enzymes in the blood of farm workers. Int Arch Occup Environ Health. 1999 Mar;72(2):84-8. OBJECTIVE: To determine the effect of different durations of exposure to agricultural chemicals on the activities of the blood enzymes delta-aminolevulinic acid dehydratase (ALAD), superoxide dismutase (SOD), and cholinesterase (ChE) in tobacco field workers. During the growing season between 1994 and 1996, dermal and respiratory exposure were determined and blood samples were drawn after the following durations of field work: (1) preexposure (0 DAY); (2) after 1 day of field work (1 DAY) - workers reentered fields at 24 h after spraying of acephate and maleic hydrazide; (3) after 30 days of field work (postspraying; 30 DAYS); and (4) Postexposure - no tobacco production. |
1(0,0,0,1) | Details |
| 16611628 | Moser VC, Simmons JE, Gennings C: Neurotoxicological interactions of a five-pesticide mixture in preweanling rats. Toxicol Sci. 2006 Jul;92(1):235-45. Epub 2006 Apr 11. We have conducted interaction studies using a mixture of five organophosphorus (OP) pesticides (chlorpyrifos, diazinon, dimethoate, acephate, and malathion) in both adult (published previously) and preweanling rats using a fixed-ratio ray design. In the present study, cholinesterase inhibition and behavioral changes (motor activity, gait, and tail-pinch response) were measured in 17-day-old Long-Evans male rats following acute exposure to the OPs. |
1(0,0,0,1) | Details |
| 3608937 | Singh AK, Drewes LR: effects of low-level chronic acephate exposure in rats. Environ Res. 1987 Aug;43(2):342-9. Blood and brain samples were collected at the end of the treatment and analyzed for cholinesterase, acetylcholinesterase, and glutamic acid decarboxylase activities and catecholamine and amino acid levels. |
1(0,0,0,1) | Details |