| 17686559 |
Canistro D, Pozzetti L, Sapone A, Broccoli M, Affatato AA, Stradiotti A, Longo V, Menichini P, Barale R, Paolini M: Perturbation of murine liver cyp-superfamily of isoforms by different combinations of pesticide mixtures. Food Chem Toxicol. 2008 Jan;46(1):34-42. Epub 2007 Jun 28.
It was previously found that fenarimol, vinclozolin or acephate, three of the most used pesticides worldwide, provoked a marked perturbation of murine cytochrome P450 (CYP)-linked monooxygenases. |
31(0,1,1,1) |
Details |
| 16190021 |
Bebe FN, Panemangalore M: Pesticides and essential minerals modify endogenous antioxidants and cytochrome P450 in tissues of rats. J Environ Sci Health B. 2005;40(5):769-84.
In both experiments, six rats/group were fed diets based on the AIN-93M diet (Control) or the same modified to contain either 500 mg calcium (Low Ca), 7 mg Zn (Low Zn): 2 mg copper (Low Cu), 60 mg zinc (High Zn) or 12 mg copper (High Cu) in the following combination: Control, LCa/LZn, LCa/LZn/LCu, or HZn/HCu, with and without a pesticide mixture containing acephate, endosulfan, and thiram at 25% LD50 for four or two weeks. |
2(0,0,0,2) |
Details |