| Name | Acetylcholinesterase |
|---|---|
| Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
| Name | HCH |
|---|---|
| CAS | 1,2,3,4,5,6-hexachlorocyclohexane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9989472 | Sahoo A, Samanta L, Das A, Patra SK, Chainy GB: Hexachlorocyclohexane-induced behavioural and neurochemical changes in rat. J Appl Toxicol. 1999 Jan-Feb;19(1):13-8. Effect of chronic oral exposure (10 and 20 mg kg (-1) body wt. for 7, 15 and 30 days) to hexachlorocyclohexane (HCH) on open-field behaviour and activities of cerebral Na+,K+-ATPase, Mg2+-ATPase and acetylcholinesterase (AChE) of rat was evaluated. |
7(0,0,1,2) | Details |
| 2626444 | Sweeney JE, Puttfarcken PS, Coyle JT: Galanthamine, an acetylcholinesterase inhibitor: a time course of the effects on performance and neurochemical parameters in mice. Pharmacol Biochem Behav. 1989 Sep;34(1):129-37. Galanthamine concentrations up to 1 x 10 (-5) M did not affect choline acetyltransferase (ChAT) activity, [3H] hemicholinium-3 (HCh-3) binding to the carrier, [3H] quinuclidinylbenzilate (QNB) binding to muscarinic receptors, or [3H] binding to nicotinic receptors in cortical homogenates. |
4(0,0,0,4) | Details |
| 1714421 | Dikshith TS, Raizada RB, Singh V, Pandey M, Srivastava MK: Repeated dermal toxicity of technical HCH and methyl parathion (50EC) to female rats (Rattus norvigicus). Indian J Exp Biol. 1991 Feb;29(2):149-55. Repeated dermal application of hexachlorocyclohexane (HCH; 100 mg/kg/day) or methyl parathion (2 mg/kg/day) individually or in combination for 7, 15 and 30 days produced pathomorphological changes in skin, liver, kidney and brain of female rats along with significant enzymatic alterations in the activity of transaminase, alkaline phosphatase lactic dehydrogenase and acetylcholinesterase. |
6(0,0,1,1) | Details |
| 7685730 | Agrawal D, Sultana P: Biochemical and structural alterations in rat erythrocytes due to hexachlorocyclohexane exposure. Food Chem Toxicol. 1993 Jun;31(6):443-8. The changes in biochemical constituents of rat erythrocyte membranes were observed after a single ip exposure to 300 mg commercial HCH/kg body weight (one-third of the LD50). The phospholipid:cholesterol ratio was altered, and there were changes in the activities of the membrane-bound enzymes ATPase and acetylcholinesterase. |
2(0,0,0,2) | Details |
| 9865422 | Bhalla P, Agrawal D: Alterations in rat erythrocyte membrane due to hexachlorocyclohexane (technical) exposure. Hum Exp Toxicol. 1998 Nov;17(11):638-42. Administration of HCH (technical) to rats at 5 mg/kg, orally, 5 days a week for 1, 2 and 3 months caused marked increase in erythrocyte membrane fluidity, osmotic fragility and decrease in levels of Na+, K (+)-ATPase, acetylcholinesterase in erythrocytes and in blood. 2. |
1(0,0,0,1) | Details |