| Name | epidermal growth factor |
|---|---|
| Synonyms | EGF; Epidermal growth factor; Pro epidermal growth factor; Pro epidermal growth factor precursor; URG; Urogastrone; epidermal growth factor (beta urogastrone); Epidermal growth factors… |
| Name | HCH |
|---|---|
| CAS | 1,2,3,4,5,6-hexachlorocyclohexane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12439862 | Hatakeyama M, Zou E, Matsumura F: Comparison of the characteristic of estrogenic action patterns of beta-HCH and heregulin beta1 in MCF-7 human breast cancer cells. J Biochem Mol Toxicol. 2002;16(5):209-19. In this study, we compared the estrogenic action pattern of beta-HCH to another ErbB2 activating agent, heregulin beta1 (HRG), along with 17beta- and epidermal growth factor, to understand the similarities and differences of their action mechanisms. |
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| 1709063 | Tsai WH, Michalopoulos GK: Responsiveness of hepatocytes to epidermal growth factor, transforming growth factor-beta and during treatment with xenobiotic hepatic tumor promoters. Cancer Lett. 1991 Apr;57(1):83-90. |
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| 20206645 | Silva E, Kabil A, Kortenkamp A: Cross-talk between non-genomic and genomic signalling pathways - Distinct effect profiles of environmental estrogens. Toxicol Appl Pharmacol. 2010 Mar 4. We investigated how activation of this pathway by E2, the estrogenic environmental contaminants o,p'-DDT, beta-HCH and p,p'-DDE, and epidermal growth factor (EGF) influences the expression of estrogen receptor (ER) target genes, such as TFF1, ER, PR, BRCA1 and CCND1, and the proliferation of breast cancer cells. |
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| 8861940 | Hishida R, Ishihara T, Kondo K, Katsura I: hch-1, a gene required for normal hatching and normal migration of a neuroblast in C. elegans, encodes a protein related to TOLLOID and BMP-1. EMBO J. 1996 Aug 15;15(16):4111-22. First, they contain the astacin metalloprotease domain, the CUB domain and the epidermal growth factor-like domain. |
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| 1715812 | Tsai WH, Zarnegar R, Michalopoulos GK: Long-term treatment with hepatic tumor promoters inhibits mitogenic responses of hepatocytes to acidic fibroblast growth factor and hepatocyte growth factor. Cancer Lett. 1991 Aug;59(2):103-8. These four mitogens are epidermal growth factor (EGF), acidic fibroblast growth factor (aFGF), hepatopoietin A/hepatocyte growth factor (HPTA/HGF) and hepatopoietin B (HPTB). |
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| 15866474 | Gomez Gallego S, Loukas A, Slade RW, Neva FA, Varatharajalu R, Nutman TB, Brindley PJ: Identification of an astacin-like metallo-proteinase transcript from the infective larvae of Strongyloides stercoralis. Parasitol Int. 2005 Jun;54(2):123-33. Epub 2005 Mar 29. In addition, the Strongyloides enzyme, designated strongylastacin, includes a central epidermal growth factor (EGF) domain followed by a carboxyl CUB (complement sub component C1r/C1s/embryonic sea urchin protein Uegf/bone morphogenetic protein) domain. |
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