Protein Information

Name STAT1
Synonyms ISGF 3; STAT 1; STAT1; STAT91; Signal transducer and activator of transcription 1; Signal transducer and activator of transcription 1 alpha/beta; Transcription factor ISGF 3; Transcription factor ISGF 3 components p91/p84…

Compound Information

Name HCH
CAS 1,2,3,4,5,6-hexachlorocyclohexane

Reference List

PubMed Abstract RScore(About this table)
17561467 Harada D, Yamanaka Y, Ueda K, Nishimura R, Morishima T, Seino Y, Tanaka H: Sustained phosphorylation of mutated FGFR3 is a crucial feature of genetic dwarfism and induces apoptosis in the ATDC5 chondrogenic cell line via PLCgamma-activated STAT1. Bone. 2007 Aug;41(2):273-81. Epub 2007 Feb 9.

6(0,0,0,6) Details
20034074 Martinez-Frias ML, de Frutos CA, Bermejo E, Nieto MA: Review of the recently defined molecular mechanisms underlying thanatophoric dysplasia and their potential therapeutic implications for achondroplasia. Am J Med Genet A. 2010 Jan;152A(1):245-55.


The signal transducers and activators of transcription (STAT1) pathway is involved in the inhibition of chondrocyte proliferation, and the mitogen-activated protein kinase (MAPK) pathways are involved in chondrocyte differentiation.
1(0,0,0,1) Details